User profiles for Hin C. Lee

Hin C Lee

University of Toronto McLaughlin Centre
Verified email at utoronto.ca
Cited by 654

The targeting pathway of Escherichia coli presecretory and integral membrane proteins is specified by the hydrophobicity of the targeting signal

HC Lee, HD Bernstein - Proceedings of the National …, 2001 - National Acad Sciences
Previous studies have demonstrated that presecretory proteins such as maltose binding
protein (MBP) and outer membrane protein A (OmpA) are targeted to the Escherichia coli inner …

The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants

…, FW Keeley, RA Cook, M Fiume, HC Lee… - Cmaj, 2018 - Can Med Assoc
BACKGROUND: The Personal Genome Project Canada is a comprehensive public data
resource that integrates whole genome sequencing data and health information. We describe …

[HTML][HTML] Trigger factor retards protein export in Escherichia coli

HC Lee, HD Bernstein - Journal of Biological Chemistry, 2002 - ASBMB
Trigger factor (TF) is a ribosome-associated protein that interacts with a wide variety of nascent
polypeptides inEscherichia coli. Previous studies have indicated that TF cooperates with …

[HTML][HTML] Anaplasma phagocytophilum-induced gene expression in both human neutrophils and HL-60 cells

HC Lee, M Kioi, J Han, RK Puri, JL Goodman - Genomics, 2008 - Elsevier
Anaplasma phagocytophilum (Ap), the etiologic agent of the tick-borne disease human
granulocytic anaplasmosis, is an obligate intracellular pathogen unique in its ability to target and …

[HTML][HTML] Anaplasma phagocytophilum causes global induction of antiapoptosis in human neutrophils

HC Lee, JL Goodman - Genomics, 2006 - Elsevier
Anaplasma phagocytophilum (Ap), the agent of the tick-borne disease human granulocytic
anaplasmosis, is an obligate intracellular pathogen unique in its ability to target and replicate …

Relation of sex to morbidity and mortality in patients with heart failure and reduced or preserved left ventricular ejection fraction

F Alla, AY Al-Hindi, CR Lee, TA Schwartz… - American Heart …, 2007 - Elsevier
BACKGROUND: Previous studies indicate a survival advantage for women over men with
chronic heart failure associated with reduced or preserved ejection fraction. Whether women …

Proteasome inhibition: a new therapeutic strategy to cancer treatment

WKK Wu, CH Cho, CW Lee, K Wu, D Fan, J Yu… - Cancer letters, 2010 - Elsevier
The ubiquitin–proteasome system is a major pathway for protein degradation. Targeting this
pathway using proteasome inhibitors represents a novel approach for the treatment of …

Prenatal genomic microarray and sequencing in Canadian medical practice: towards consensus

…, D Chitayat, E Kolomietz, HC Lee… - Journal of Medical …, 2015 - jmg.bmj.com
The University of Toronto’s McLaughlin Centre invited medical genetics professionals and
international advisors to consider the challenges in applying new genome-wide technologies …

NTIRE 2021 challenge on image deblurring

…, L Sun, J Tang, J Pan, D Lee, C Lee… - Proceedings of the …, 2021 - openaccess.thecvf.com
Motion blur is a common photography artifact in dynamic environments that typically comes
jointly with the other types of degradation. This paper reviews the NTIRE 2021 Challenge on …

[HTML][HTML] Antibiotic management of complicated intra-abdominal infections in adults: The Asian perspective

…, B Sirichindakul, T Tantawichien, CKC Lee… - Annals of Medicine and …, 2014 - Elsevier
Regional epidemiological data and resistance profiles are essential for selecting appropriate
antibiotic therapy for intra-abdominal infections (IAIs). However, such information may not …