Background— Less than one-third of smokers hospitalized with an acute coronary syndrome
(ACS) remain abstinent following discharge. We assessed whether varenicline, begun in-…

Ventricular arrhythmias are common in patients with congestive heart failure (CHF) and may
be exacerbated by positive inotropic therapy. Because human B-type natriuretic peptide (…

BACKGROUND: Patients who continue to smoke after acute coronary syndrome are at
increased risk of reinfarction and death. We previously found use of varenicline to increase …

Background Intravenous infusion of nesiritide, a brain (B-type) natriuretic peptide, has
beneficial hemodynamic effects in patients with decompensated congestive heart failure. We …

Importance Differences in clinical profiles, outcomes, and diuretic treatment effects may
exist between patients with de novo heart failure (HF) and worsening chronic HF (WHF). …

Importance Although furosemide is the most commonly used loop diuretic in patients with
heart failure, some studies suggest a potential benefit for torsemide. Objective To determine …

Objectives : This study sought to assess the acute hemodynamic effect of vasopressin V 2
receptor antagonism. Background : In decompensated heart failure (HF), tolvaptan, a …

Objectives. We sought to document the common mechanisms of the antiatherogenic effects
of the cholesterol-lowering hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase …

Background : In patients with acute heart failure (AHF), dyspnea relief is the most immediate
goal. Renal dysfunction, diuretic resistance, and hyponatremia represent treatment …

Atherosclerosis is increasingly thought to be a chronic inflammatory disease. Inflammation
requires transmigration of leukocytes from the circulation to the tissues. Adhesion of …