Comparison of the effects of glucagon-like peptide receptor agonists and sodium-glucose cotransporter 2 inhibitors for prevention of major adverse cardiovascular and …

…, DL Bhatt, LA Leiter, DK McGuire, JPH Wilding… - Circulation, 2019 - Am Heart Assoc
… established atherosclerotic cardiovascular disease (HR, 0.86; 95… (HR, 1.01; 95% CI, 0.87–1.19;
P=0.81; P interaction, 0.028). SGLT2i reduced hospitalization for heart failure by 31% (HR

Effect of dapagliflozin on heart failure and mortality in type 2 diabetes mellitus

…, DL Bhatt, LA Leiter, DK McGuire, JPH Wilding… - Circulation, 2019 - Am Heart Assoc
… , 0.76 [95% CI, 0.62–0.92]), it reduced cardiovascular death only in patients with HFrEF (HR, …
Dr Wilding reports personal fees and other from Brigham and Women’s Hospital; grants, …

Phase I clinical and pharmacokinetic study of an one-hour infusion of ormaplatin (NSC 363812)

…, HI Robins, DR Spriggs, G Wilding - Investigational new …, 1999 - Springer
Ormaplatin (NSC 363812, tetraplatin) is a stable platinum (IV) analog which has exhibited
activity against cisplatin-resistant cell lines. A phase I trial of ormaplatin administered as a 1-h …

The protective effect of profound hypothermia on the canine central nervous system during one hour of circulatory arrest

JV O'Connor, T Wilding, P Farmer, J Sher… - The Annals of thoracic …, 1986 - Elsevier
… protocol but without the one-hour period of circulatory arrest. … We conclude that one hour
of circulatory arrest under … survival in dogs that underwent one hour of circulatory arrest at 0…

Accidents involving off-road motor vehicles in a northern community.

P Hasselback, HR Wilding - CMAJ: Canadian Medical Association …, 1987 - ncbi.nlm.nih.gov
The increasing number of accidents associated with off-road motor vehicles used for
recreational purposes prompted this prospective study. During 1985 the records of victims of all …

Dapagliflozin and cardiac, kidney, and limb outcomes in patients with and without peripheral artery disease in DECLARE-TIMI 58

…, RH De Mendonca Furtado, JPH Wilding… - Circulation, 2020 - Am Heart Assoc
… For the analysis of natural history evaluating the risk of outcomes comparing patients with
and without PAD, a multivariable-adjusted HR was obtained from a Cox model that included …

Effect of dapagliflozin on atrial fibrillation in patients with type 2 diabetes mellitus: insights from the DECLARE-TIMI 58 trial

…, DL Bhatt, LA Leiter, DK McGuire, JPH Wilding… - Circulation, 2020 - Am Heart Assoc
… Similarly, presence of atherosclerotic cardiovascular disease (HR, 0.83 [95% CI, 0.66–1.04])
versus multiple risk factors (HR, 0.78 [95% CI, 0.62–0.99]; P for interaction 0.72) or a history …

SGLT-2 inhibitors and cardiovascular risk: an analysis of CVD-REAL

…, KI Birkeland, ME Jørgensen, JP Wilding… - Journal of the American …, 2018 - jacc.org
… to reduce the risk of death (HR: 0.68) and hospitalization for HF (HR: 0.65). All patients …
significant reduction seen in the subgroup without established CVD (HR: 0.98; 95% CI: 0.74 to …

Lower risk of heart failure and death in patients initiated on SGLT-2 inhibitors versus other glucose-lowering drugs: the CVD-REAL study.

…, MA Cavender, AZ Fu, JP Wilding… - …, 2017 - livrepository.liverpool.ac.uk
Background -Reduction in cardiovascular death and hospitalization for heart failure (HHF)
was recently reported with the sodium-glucose co-transporter-2 inhibitor (SGLT-2i) …

Gastrointestinal transit and systemic absorption of captopril from a pulsed-release formulation

IR Wilding, SS Davis, M Bakhshaee… - Pharmaceutical …, 1992 - Springer
… Each volunteer drank approximately 100 ml of water every hour postdose for the first 4 hr.
A standard lunch and dinner were provided at 4 and 9 hr postdose, respectively. Fluid was …