Traumatic brain injury (TBI) has the highest incidence of all common neurological disorders,
and poses a substantial public health burden. TBI is increasingly documented not only as …

Vaginitis is one of the most common problems in clinical medicine, and it is the reason cited
most often for visits to obstetricians and gynecologists. This article reviews the epidemiology …

The BAR (Bin/amphiphysin/Rvs) domain is the most conserved feature in amphiphysins from
yeast to human and is also found in endophilins and nadrins. We solved the structure of the …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
dramatically expedited global vaccine development efforts 1 , 2 – 3 , most targeting the viral ‘spike’ …

… Cryopreserved human PBMC were thawed and rested for 4 h at 37 C. Cells were cultured
in 96-well plates at 1 × 10 6 cells/well and stimulated for 20 h with 2 μg/peptide/mL of peptide …

AP2 is the best-characterized member of the family of heterotetrameric clathrin adaptor
complexes that play pivotal roles in many vesicle trafficking pathways within the cell. AP2 …

Endophilin‐A1 is a BAR domain‐containing protein enriched at synapses and is implicated
in synaptic vesicle endocytosis. It binds to dynamin and synaptojanin via a C‐terminal SH3 …

Importin β family transport receptors shuttle between the nucleus and the cytoplasm and
mediate transport of macromolecules through nuclear pore complexes (NPCs). The interactions …

A spectrum of membrane curvatures exists within cells, and proteins have evolved different
modules to detect, create, and maintain these curvatures. Here we present the crystal …

Background A large, multi-province outbreak of listeriosis associated with ready-to-eat meat
products contaminated with Listeria monocytogenes serotype 1/2a occurred in Canada in …