We performed a comprehensive cognitive, neuroimaging, and genetic study of 31 patients
with primary progressive aphasia (PPA), a decline in language functions that remains isolated …

Objective: To identify and compare the patterns of cerebral atrophy associated with two clinical
variants of frontotemporal lobar degeneration (FTLD): frontotemporal dementia (FTD) and …

We report vibrational Raman and infrared spectra for chemically separated C 60 and C 70
fullerenes. Thin film samples were prepared by subliming the chromatographically separated …

Objective: To determine neural correlates of recovery from aphasia after left frontal injury.
Methods: The authors studied the verbal performance of patients with infarcts centered in the …

Importance Amyloid-β positron emission tomography (PET) imaging allows in vivo detection
of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its …

Neurodegenerative diseases are associated with profound changes in social and emotional
function. The emergence of increasingly sophisticated methods for measuring brain volume …

Neuropathological and in vivo studies have revealed a tight relationship between tau
pathology and cognitive impairment across the Alzheimer’s disease spectrum. However, tau …

Alzheimer's disease and frontotemporal dementia (FTD) can be difficult to differentiate
clinically because of overlapping symptoms. Distinguishing the two dementias based on …

Background Until recently, frontotemporal lobar degeneration (FTLD) was considered a rare
neurodegenerative disorder that was difficult to diagnose. The publication of consensus …

Objective Frontotemporal lobar degeneration (FTLD) is characterized by impairments in
social, behavioral, and/or language function, but postmortem studies indicate that multiple …