High-content screening for quantitative cell biology

MM Usaj, EB Styles, AJ Verster, H Friesen, C Boone… - Trends in cell …, 2016 - cell.com
High-content screening (HCS), which combines automated fluorescence microscopy with
quantitative image analysis, allows the acquisition of unbiased multiparametric data at the …

Pho85, a multifunctional cyclin‐dependent protein kinase in budding yeast

D Huang, H Friesen, B Andrews - Molecular microbiology, 2007 - Wiley Online Library
Pho85 is a multifunctional cyclin‐dependent kinase (Cdk) in Saccharomyces cerevisiae that
has emerged as an important model for the role of Cdks in both cell cycle control and other …

Global mapping of the yeast genetic interaction network

…, M Chang, YQ Chen, X Cheng, G Chua, H Friesen… - science, 2004 - science.org
A genetic interaction network containing ∼1000 genes and ∼4000 interactions was mapped
by crossing mutations in 132 different query genes into a set of ∼4700 viable gene yeast …

A radioimmunoassay for human prolactin

P Hwang, H Guyda, H Friesen - Proceedings of the …, 1971 - National Acad Sciences
A radioimmunoassay for primate prolactin has been developed, with [ 131 I] monkey prolactin,
and antibodies to monkey or human prolactin. The assay is specific for prolactin; human …

Studies of prolactin secretion in human pregnancy

JE Tyson, P Hwang, H Guyda, HG Friesen - American journal of obstetrics …, 1972 - Elsevier
Recent studies have confirmed the presence of a separate human prolactin (HPr) molecule.
Measurement of HPr concentrations has been performed in normal and abnormal gestation …

Prolactin-secreting tumors and hypogonadism in 22 men

…, S Van Vliet, C Faiman, HG Friesen - … England Journal of …, 1978 - Mass Medical Soc
We studied 22 men with prolactin-secreting pituitary tumors and hypogonadism. Twenty
complained of impotence, nine had visual impairment, and three experienced galactorrhea. …

Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for …

…, F Talamantes, M Robertson, HG Friesen… - …, 1993 - academic.oup.com
… Ann NY Acad Sci 148501-531 Martin JM, Friesen H 1969 Effect of human placental lactogen
on the isolated islets of Langerhans … IC, Friesen HG 1990 Molecular cloning and expression …

[HTML][HTML] Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae

…, GC Hon, CL Myers, A Parsons, H Friesen… - Journal of biology, 2006 - Springer
Background The study of complex biological networks and prediction of gene function has
been enabled by high-throughput (HTP) methods for detection of genetic and protein …

[PDF][PDF] Yeast proteome dynamics from single cell imaging and automated analysis

YT Chong, JLY Koh, H Friesen, SK Duffy, MJ Cox… - Cell, 2015 - cell.com
Proteomics has proved invaluable in generating large-scale quantitative data; however, the
development of systems approaches for examining the proteome in vivo has lagged behind. …

A new sensitive and specific bioassay for lactogenic hormones: measurement of prolactin and growth hormone in human serum

…, CT BEER, RL NOBLE, HG FRIESEN - The Journal of …, 1980 - academic.oup.com
… HA, Friesen HG 1976 The purification and characterization of ovine placental lactogen.
Endocrinology 98:65 12. Tolis G, Goldstein M, Friesen HG … Shiu RPC, Kelly PA, Friesen HG 1973 …