Background Many women of reproductive age have depression, necessitating therapy with
either a tricyclic antidepressant drug or a drug, such as fluoxetine, that inhibits the reuptake …

Inhibins and activins are dimeric growth factors of the transforming growth factor-beta
superfamily, a class of peptides that can regulate the growth and differentiation of a variety of cell …

Integrin α1β1 is a collagen receptor abundantly expressed on microvascular endothelial
cells. As well as being the only collagen receptor able to activate the Ras/Shc/mitogen-activated …

Activation of integrins upon binding to extracellular matrix proteins is believed to be a crucial
step for the regulation of cell survival and proliferation. We have used integrin α1-null mice …

Objective. —To compare pregnancy outcome prospectively after phenytoin and carbamazepine
monotherapy with outcome in matched mother-child pairs exposed to nonteratogens to …

The transforming growth factor (TGF)-β-inducible integrin αvβ6 is preferentially expressed at
sites of epithelial remodeling and has been shown to bind and activate latent precursor TGF-…

Turner syndrome is the complex human phenotype associated with complete or partial
monosomy X. Principle features of Turner syndrome include short stature, ovarian failure, and a …

The AvB6 integrin is up-regulated on epithelial malignancies and has been implicated in
various aspects of cancer progression. Immunohistochemical analysis of AvB6 expression in …

Angiogenesis is essential for tumor growth and blocking this process might be a valid tool for
the control of cancer growth. We showed previously that tumor angiogenesis in integrin α1-…

IFN-γ, a pleiotropic cytokine, is a key effector molecule in the pathogenesis of several
autoimmune diseases, including lupus. Importantly, deletion of IFN-γ or IFN-γR in several lupus-…