User profiles for Gregg S. Nelson

Gregg Nelson

Professor of Obstetrics & Gynecology, University of Calgary
Verified email at ucalgary.ca
Cited by 11048

POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium

…, LN Hoang, JB McIntyre, MA Duggan, GS Nelson… - Gynecologic …, 2014 - Elsevier
Objective POLE exonuclease domain mutations were recently found to occur in a subset of
endometrial carcinomas and result in defective proof-reading function during DNA replication…

[HTML][HTML] Prognostic role and implications of mutation status of tumor suppressor gene ARID1A in cancer: a systematic review and meta-analysis

…, SY Lee, DW Kim, GM Yousef, A Scorilas, GS Nelson… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Loss of the tumor suppressor gene AT-rich interactive domain-containing protein 1A (ARID1A)
has been demonstrated in several cancers, but its prognostic role is unknown. We aimed …

Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study

…, E Hatfield, JM de Andrade, GS Nelson… - The Journal of …, 2018 - Wiley Online Library
We aimed to validate the prognostic association of p16 expression in ovarian high‐grade
serous carcinomas (HGSC) and to explore it in other ovarian carcinoma histotypes. p16 protein …

[HTML][HTML] Enhanced recovery after surgery: implementing a new standard of surgical care

…, V Samouëlian, MH Auclair, H Brar, GS Nelson - Cmaj, 2019 - Can Med Assoc
Randomized controlled trials (RCTs), systematic reviews and meta-analyses have shown
that carbohydrate loading before surgery increases insulin sensitivity, reduces postoperative …

SWI/SNF‐deficiency defines highly aggressive undifferentiated endometrial carcinoma

…, M Carey, GS Nelson, S Hamilton… - The Journal of …, 2021 - Wiley Online Library
Dedifferentiated/undifferentiated endometrial carcinoma (DDEC/UEC) is an endometrial
cancer characterized by the presence of histologically undifferentiated carcinoma. Genomic …

Quantification of ER/PR expression in ovarian low-grade serous carcinoma

…, M Dean, P Chu, JG Nation, GS Nelson… - Gynecologic …, 2013 - Elsevier
OBJECTIVE: Case reports suggest that hormonal therapy may be a useful treatment option
for low-grade serous carcinomas (LGSC) but the clinical value remains uncertain. We …

Equivalent survival of p53 mutated endometrial endometrioid carcinoma grade 3 and endometrial serous carcinoma

…, P Ghatage, BA Clarke, GS Nelson… - International Journal …, 2021 - journals.lww.com
TP53 status is the most important prognostic biomarker in endometrial carcinoma. We asked
the question whether p53 mutated endometrial endometrioid carcinomas grade 3 (EEC3) or …

p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study

…, PF Rambau, CH Lee, GS Nelson… - The Journal of …, 2023 - Wiley Online Library
Our objective was to test whether p53 expression status is associated with survival for
women diagnosed with the most common ovarian carcinoma histotypes (high‐grade serous …

Immunohistochemical profiling of endometrial serous carcinoma

…, A Husain, GS Nelson, PF Rambau, S Liu… - International Journal …, 2017 - journals.lww.com
Endometrial serous carcinoma (ESC) is an aggressive neoplasm mainly seen in older
women. The objective of this study was to refine immunohistochemical (IHC) panels for the …

[HTML][HTML] The diagnostic utility of TP53 and CDKN2A to distinguish ovarian high-grade serous carcinoma from low-grade serous ovarian tumors

AD Altman, GS Nelson, P Ghatage, JB McIntyre… - Modern Pathology, 2013 - Elsevier
Low-grade serous carcinomas and serous borderline tumors, combined herein and referred
to as low-grade serous tumors, show distinct molecular alterations and clinical behaviors …