User profiles for Graeme Schwindt

Graeme Schwindt

Verified email at utoronto.ca
Cited by 715

Functional imaging studies of episodic memory in Alzheimer's disease: a quantitative meta-analysis

GC Schwindt, SE Black - Neuroimage, 2009 - Elsevier
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder, rapidly increasing in
prevalence as the population ages. As the potential for disease-modifying therapy grows, a …

Whole‐brain white matter disruption in semantic and nonfluent variants of primary progressive aphasia

GC Schwindt, NL Graham, E Rochon… - Human brain …, 2013 - Wiley Online Library
Semantic (svPPA) and nonfluent (nfPPA) variants of primary progressive aphasia are
associated with distinct patterns of cortical atrophy and underlying pathology. Little is known, …

Functional specificity of the visual word form area: general activation for words and symbols but specific network activation for words

K Reinke, M Fernandes, G Schwindt, K O'Craven… - Brain and language, 2008 - Elsevier
The functional specificity of the brain region known as the Visual Word Form Area (VWFA)
was examined using fMRI. We explored whether this area serves a general role in processing …

Chronic vagus nerve stimulation for treatment-resistant depression decreases resting ventromedial prefrontal glucose metabolism

JV Pardo, SA Sheikh, GC Schwindt, JT Lee… - Neuroimage, 2008 - Elsevier
Vagus nerve stimulation (VNS) is used as an adjunctive therapy for treatment-resistant
depression (TRD). Its mechanism of action is not fully understood. Longitudinal measurement of …

Validation of the triage risk stratification tool to identify older persons at risk for hospital admission and returning to the emergency department

JS Lee, G Schwindt, M Langevin… - Journal of the …, 2008 - Wiley Online Library
OBJECTIVES: To assess the predictive validity of the Triage Risk Stratification Tool (TRST)
to identify return to the emergency department (ED) or hospitalization in a multicenter patient …

Enhancement of automated blood flow estimates (ENABLE) from arterial spin‐labeled MRI

…, MA Chappell, J Ramirez, G Schwindt… - Journal of Magnetic …, 2018 - Wiley Online Library
Purpose To validate a multiparametric automated algorithm—ENhancement of Automated
Blood fLow Estimates (ENABLE)—that identifies useful and poor arterial spin‐labeled (ASL) …

Modulation of the default-mode network between rest and task in Alzheimer's Disease

GC Schwindt, S Chaudhary, D Crane, A Ganda… - Cerebral …, 2013 - academic.oup.com
Default-mode network (DMN) connectivity at rest is disrupted in Alzheimer's Disease (AD),
but it is unknown whether this abnormality is a static feature, or if it varies across cognitive …

Hemodynamic effects of cholinesterase inhibition in mild Alzheimer's disease

S Chaudhary, A Scouten, G Schwindt… - Journal of Magnetic …, 2013 - Wiley Online Library
Purpose To evaluate the spatiotemporal progression of perfusion changes in early stages of
Alzheimer's disease (AD), we imaged the perfusion response to pharmacological treatment …

[HTML][HTML] Attenuation of functional hyperemia to visual stimulation in mild Alzheimer's disease and its sensitivity to cholinesterase inhibition

…, S Chaudhary, A Dorr, A Scouten, G Schwindt… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Despite the growing recognition of the significance of cerebrovascular impairment in the
etiology and progression of Alzheimer's disease (AD), the early stage brain vascular dysfunction …

[HTML][HTML] A preliminary study of resting brain metabolism in treatment-resistant depression before and after treatment with olanzapine-fluoxetine combination

JV Pardo, SA Sheikh, G Schwindt, JT Lee, DE Adson… - Plos one, 2020 - journals.plos.org
Treatment-resistant depression (TRD) occurs in many patients and causes high morbidity and
mortality. Because TRD subjects are particularly difficult to study especially longitudinally, …