Background We evaluated whether rivaroxaban alone or in combination with aspirin would
be more effective than aspirin alone for secondary cardiovascular prevention. Methods In this …

Background Prospective studies suggest that hyperinsulinemia may be an important risk factor
for ischemic heart disease. However, it has not been determined whether plasma insulin …

Background Three different glucagon-like peptide-1 (GLP-1) receptor agonists reduce
cardiovascular outcomes in people with type 2 diabetes at high cardiovascular risk with high …

Background Case-control studies have reported that patients with ischemic heart disease (IHD)
have a higher proportion of small, dense LDL particles than do healthy control subjects. …

… Dagenais GR, … Gömöri K, Herwig M, Hassoun R, Budde H, Mostafi N, Delalat S, Modi S,
Begovic M, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Kovács Á, Mügge A …

Background Patients with peripheral artery disease have an increased risk of cardiovascular
morbidity and mortality. Antiplatelet agents are widely used to reduce these complications. …

Importance The prevalence of cardiometabolic multimorbidity is increasing. Objective To
estimate reductions in life expectancy associated with cardiometabolic multimorbidity. Design, …

Background To help adapt cardiovascular disease risk prediction approaches to low-income
and middle-income countries, WHO has convened an effort to develop, evaluate, and …

Background To our knowledge, no previous study has prospectively documented the
incidence of common diseases and related mortality in high-income countries (HICs), middle-…

Background Angiotensin-converting-enzyme (ACE) inhibitors reduce cardiovascular
mortality and morbidity in patients with heart failure or left ventricular systolic dysfunction (LVSD). …