[HTML][HTML] Genetic associations with valvular calcification and aortic stenosis

G Thanassoulis, CY Campbell, DS Owens… - … England Journal of …, 2013 - Mass Medical Soc
Background Limited information is available regarding genetic contributions to valvular
calcification, which is an important precursor of clinical valve disease. Methods We determined …

2016 Canadian Cardiovascular Society guidelines for the management of dyslipidemia for the prevention of cardiovascular disease in the adult

…, JL Sievenpiper, JA Stone, G Thanassoulis… - Canadian Journal of …, 2016 - Elsevier
Since the publication of the 2012 guidelines new literature has emerged to inform decision-making.
The 2016 guidelines primary panel selected a number of clinically relevant …

NHLBI working group recommendations to reduce lipoprotein (a)-mediated risk of cardiovascular disease and aortic stenosis

…, G Reyes-Soffer, RD Santos, G Thanassoulis… - Journal of the American …, 2018 - jacc.org
Pathophysiological, epidemiological, and genetic studies provide strong evidence that
lipoprotein(a) [Lp(a)] is a causal mediator of cardiovascular disease (CVD) and calcific aortic …

Outcomes in adults with bicuspid aortic valves

N Tzemos, J Therrien, J Yip, G Thanassoulis… - Jama, 2008 - jamanetwork.com
Context Bicuspid aortic valve is the most common congenital cardiac anomaly in the adult
population. Cardiac outcomes in a contemporary population of adults with bicuspid aortic …

[HTML][HTML] Vitamin D and risk of multiple sclerosis: a Mendelian randomization study

…, A Leong, CMT Greenwood, G Thanassoulis… - PLoS …, 2015 - journals.plos.org
Background Observational studies have demonstrated an association between decreased
vitamin D level and risk of multiple sclerosis (MS); however, it remains unclear whether this …

Pericardial fat is associated with prevalent atrial fibrillation: the Framingham Heart Study

G Thanassoulis, JM Massaro… - Circulation …, 2010 - Am Heart Assoc
Background— Obesity represents an important risk factor for atrial fibrillation (AF). We
tested the hypothesis that pericardial fat, a unique fat deposit in close anatomic proximity to …

2021 Canadian Cardiovascular Society guidelines for the management of dyslipidemia for the prevention of cardiovascular disease in adults

GJ Pearson, G Thanassoulis, TJ Anderson… - Canadian journal of …, 2021 - Elsevier
The 2021 guidelines primary panel selected clinically relevant questions and produced
updated recommendations, on the basis of important new findings that have emerged since the …

Apolipoprotein B particles and cardiovascular disease: a narrative review

AD Sniderman, G Thanassoulis, T Glavinovic… - JAMA …, 2019 - jamanetwork.com
Importance The conventional model of atherosclerosis presumes that the mass of cholesterol
within very low-density lipoprotein particles, low-density lipoprotein particles, chylomicron, …

Sex versus gender-related characteristics: which predicts outcome after acute coronary syndrome in the young?

…, KH Humphries, CM Norris, G Thanassoulis… - Journal of the American …, 2016 - jacc.org
Background : “Gender” reflects social norms for women and men, whereas “sex” defines
biological characteristics. Gender-related characteristics explain some differences in access to …

A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study

G Thanassoulis, GM Peloso, MJ Pencina… - Circulation …, 2012 - Am Heart Assoc
Background— Limited data exist regarding the use of a genetic risk score (GRS) for predicting
risk of incident cardiovascular disease (CVD) in US-based samples. Methods and Results…