Objective To determine the point at which differences in clinical assessment scores on
physical ability, pain and overall condition are sufficiently large to correspond to a subjective …

144 patients with severe rheumatoid arthritis from six centres were randomised to receive
oral cyclosporin or placebo for 6 months. The initial daily dose of cyclosporin was 2·5 mg/kg, …

OBJECTIVE: High dose methotrexate (MTX) has been linked with bone loss in oncology
patients. However, it is unclear whether longterm low dose MTX used in the treatment of …

Objective To compare signal versus aggregate measurement strategies using the VA3. 0S
version of the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis (OA) Index…

… There was a grade 3/6 ejection systolic murmur at the base of the heart radiating up the
neck and a grade 2/6 early diastolic blowing murmur at the left sternal border. There was no …

… Patients assessed as having an OA grade of 2 or 3 on their study joint made up 94.5% of
randomly assigned patients. Twenty-five patients withdrew after random assignment (15 due to …

Objective To conduct the first Canadian study of the comparative efficacy and safety of
tenoxicam and diclofenac in patients with primary osteoarthritis (OA) of the knee. Methods …

… 5, grade 0 being normal, grade 1 slight changes, grade 2 definite changes, grade 3 minimum
destructive changes, grade 4severe destructive changes, and grade 5 mutilating changes. …

In an extensive pathological collection in the Royal Infirmary at the University of Glasgow,
there are a large number of bone and joint specimens of considerable interest1. One of these, …

Objective To conduct the first Canadian study of the comparative efficacy and safety of
nabumetone and diclofenac SR in patients with primary osteoarthritis (OA) of the hip, knee and …