The ethically trained physician: myth or reality?

GK Balkos - Canadian Medical Association Journal, 1983 - ncbi.nlm.nih.gov
Through a questionnaire distributed to 300 physicians in the Toronto area, three aspects of
their ethical awareness were examined: the formal codes, the need for consultation in …

[HTML][HTML] TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer

NE Bhola, JM Balko, TC Dugger… - The Journal of …, 2013 - Am Soc Clin Investig
After an initial response to chemotherapy, many patients with triple-negative breast cancer (TNBC)
have recurrence of drug-resistant metastatic disease. Studies with TNBC cells …

[HTML][HTML] Phosphatidylinositol 3-kinase and antiestrogen resistance in breast cancer

TW Miller, JM Balko, CL Arteaga - Journal of clinical oncology, 2011 - ncbi.nlm.nih.gov
Although antiestrogen therapies targeting estrogen receptor (ER) α signaling prevent disease
recurrence in the majority of patients with hormone-dependent breast cancer, a significant …

Lipofibromatous hamartoma of the median nerve: case report with magnetic resonance imaging correlation

M Guthikonda, SS Rengachary, MG Balko… - …, 1994 - journals.lww.com
THE AUTHORS REPORT a case of lipofibromatous hamartoma of the median nerve in a
patient who presented with symptoms of carpal tunnel syndrome. The diagnosis was made by …

Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance

JM Balko, RS Cook, DB Vaught, MG Kuba, TW Miller… - Nature medicine, 2012 - nature.com
Neoadjuvant chemotherapy (NAC) induces a pathological complete response (pCR) in ∼30%
of patients with breast cancer. However, many patients have residual cancer after …

[HTML][HTML] Multi-omics analysis identifies therapeutic vulnerabilities in triple-negative breast cancer subtypes

…, Y Ban, H Huang, L Wang, JL James, JM Balko… - Nature …, 2021 - nature.com
Triple-negative breast cancer (TNBC) is a collection of biologically diverse cancers characterized
by distinct transcriptional patterns, biology, and immune composition. TNBCs subtypes …

Superfluorescence in the presence of inhomogeneousbroadening and relaxation

B Balko, IW Kay, JD Silk, R Vuduc, JW Neuberger - Hyperfine interactions, 1997 - Springer
In this paper we show how inhomogeneous broadening produces dephasing, inhibits cooperative
emission and thus reduces the intensity of the SF pulse. We also show how electronic …

Crystallinity of poly (3‐hexylthiophene) in thin films determined by fast scanning calorimetry

J Balko, A Rinscheid, A Wurm, C Schick… - Journal of Polymer …, 2016 - Wiley Online Library
Using fast scanning calorimetry, we determined the crystallinity of thin films of poly(3‐hexylthiophene)
crystallized from the melt from measurements of the specific melting enthalpy. A …

[HTML][HTML] Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

…, P Ericsson-Gonzalez, P Charoentong, J Balko… - Genome medicine, 2019 - Springer
We introduce quanTIseq, a method to quantify the fractions of ten immune cell types from bulk
RNA-sequencing data. quanTIseq was extensively validated in blood and tumor samples …

Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence

JM Balko, LJ Schwarz, N Luo, MV Estrada… - Science translational …, 2016 - science.org
Amplifications at 9p24 have been identified in breast cancer and other malignancies, but the
genes within this locus causally associated with oncogenicity or tumor progression remain …