Randomized controlled trials have shown a reduction in platelet alloimmunization and
refractoriness in patients with acute leukemia (AL) with the use of poststorage leukoreduction of …

Previous studies have suggested that desmopressin may reduce the bleeding diathesis that
often complicates open-heart surgery. To pursue this question further, we performed a …

Piperacillin as a single agent was compared in a prospective randomized trial with
carboxypenicillin-aminoglycoside combinations in empirical therapy of serious bacterial infections. …

BACKGROUND: Canada's publicly funded blood system has recently introduced high‐purity
concentrates as the standard treatment for individuals with hemophilia. The added cost and …

RODENTICIDES often contain warfarin or warfarinlike compounds as their active ingredient.
The anticoagulant effects of human rodenticide poisoning do not, however, necessarily …

Three patients developed severe but self‐limited hemolytic anemia within 2 weeks of renal
transplantation. All three had received kidneys from cadaver donors who were blood group O…

A BamHI polymorphism has been identified in the human factor IX gene. This polymorphism,
which occurs in approximately 6% of X chromosomes, has been used to determine the …

BACKGROUND: Bleeding complications and blood product consumption have been a major
concern during liver transplantation. Prevention of plasminogen activation and fibrinolysis …

Six hemophilia patients previously seronegative for human immunodeficiency virus (HIV)
seroconverted between September 1986 and September 1987. None had risk factors for HIV …

The heterogeneity of pyruvate kinase (PK) deficiency associated with hereditary haemolytic
anaemia is emphasized by studies of a kindred harbouring two distinct mutant forms of this …