User profiles for G. Clarkson
Gavin ClarksonFormer Deputy Assistant Secretary for Policy and Economic Development -- Indian Affairs Verified email at Clarkson.LLC Cited by 1282 |
Synthesis of neoglycopolymers by a combination of “click chemistry” and living radical polymerization
V Ladmiral, G Mantovani, GJ Clarkson… - Journal of the …, 2006 - ACS Publications
The synthesis of novel well-defined alkyne side chain functional polymers featuring narrow
molecular weight distributions (PDI = 1.09−1.17) by living radical polymerization is described. …
molecular weight distributions (PDI = 1.09−1.17) by living radical polymerization is described. …
Organometallic half-sandwich iridium anticancer complexes
…, L Salassa, PCA Bruijnincx, GJ Clarkson… - Journal of medicinal …, 2011 - ACS Publications
… This result is consistent with the replication mapping experiments (Figure 4), which show
that G residues are the preferential binding sites on polymeric DNA modified with complexes 4−…
that G residues are the preferential binding sites on polymeric DNA modified with complexes 4−…
Targeted photoredox catalysis in cancer cells
Hypoxic tumours are a major problem for cancer photodynamic therapy. Here, we show that
photoredox catalysis can provide an oxygen-independent mechanism of action to combat …
photoredox catalysis can provide an oxygen-independent mechanism of action to combat …
The potent oxidant anticancer activity of organoiridium catalysts
…, NPE Barry, AM Pizarro, GJ Clarkson… - Angewandte …, 2014 - Wiley Online Library
Platinum complexes are the most widely used anticancer drugs; however, new generations
of agents are needed. The organoiridium(III) complex [(η 5 ‐Cp xbiph )Ir(phpy)(Cl)] (1‐Cl), …
of agents are needed. The organoiridium(III) complex [(η 5 ‐Cp xbiph )Ir(phpy)(Cl)] (1‐Cl), …
A class of ruthenium (II) catalyst for asymmetric transfer hydrogenations of ketones
AM Hayes, DJ Morris, GJ Clarkson… - Journal of the American …, 2005 - ACS Publications
Ruthenium dimer 6 (readily available in two steps from TsDPEN) is converted directly to
monomeric asymmetric transfer hydrogenation catalyst 3 in situ under the conditions employed …
monomeric asymmetric transfer hydrogenation catalyst 3 in situ under the conditions employed …
A new class of “tethered” ruthenium (II) catalyst for asymmetric transfer hydrogenation reactions
J Hannedouche, GJ Clarkson… - Journal of the American …, 2004 - ACS Publications
Ruthenium dimer 4 is converted directly to monomeric asymmetric transfer hydrogenation
catalyst 2 under the conditions employed for ketone reduction. Using 0.25 mol % of either 4 or …
catalyst 2 under the conditions employed for ketone reduction. Using 0.25 mol % of either 4 or …
A Potent Trans‐Diimine Platinum Anticancer Complex Photoactivated by Visible Light
Platin mit Licht aktiviert: Der inerte Pt IV‐Diazidokomplex trans, trans, trans‐[Pt (N 3) 2 (OH)
2 (py) 2] verwandelt sich bei der Bestrahlung mit geringen Dosen sichtbaren Lichts in einen …
2 (py) 2] verwandelt sich bei der Bestrahlung mit geringen Dosen sichtbaren Lichts in einen …
Chunks in expert memory: Evidence for the magical number four… or is it two?
F Gobet, G Clarkson - Memory, 2004 - Taylor & Francis
This study aims to test the divergent predictions of the chunking theory (Chase & Simon, 1973)
and template theory (Gobet & Simon, 1996a, 2000) with respect to the number of chunks …
and template theory (Gobet & Simon, 1996a, 2000) with respect to the number of chunks …
Optically pure, water-stable metallo-helical 'flexicate'assemblies with antibiotic activity
SE Howson, A Bolhuis, V Brabec, GJ Clarkson… - Nature …, 2012 - nature.com
The helicates—chiral assemblies of two or more metal atoms linked by short or relatively
rigid multidentate organic ligands—may be regarded as non-peptide mimetics of α-helices …
rigid multidentate organic ligands—may be regarded as non-peptide mimetics of α-helices …
Asymmetric transfer hydrogenation by synthetic catalysts in cancer cells
…, I Romero-Canelón, C Sanchez-Cano, GJ Clarkson… - Nature …, 2018 - nature.com
Catalytic anticancer metallodrugs active at low doses could minimize side-effects, introduce
novel mechanisms of action that combat resistance and widen the spectrum of anticancer-…
novel mechanisms of action that combat resistance and widen the spectrum of anticancer-…