In 1997, the Canadian Apheresis Group reviewed data on 103 416 plasma exchange
procedures that had been collected since 1980. Although the number of plasma exchanges …

THE acceptance of the Renaissance concept that an illness could be helped by bloodletting
was tempered by the adverse effects of blood loss. Indeed, Louis XIII and George …

Background. Thrombotic thrombocytopenic purpura is an uncommon disease with a high
mortality rate even with current treatment. The cause of the syndrome and its optimal treatment …

… In our 135 patients, the PT and PTT were normal at entry in 128 patients (Rock et al, 1998). …
In our study of 135 patients with acute TTP (Rock et al, 1991), we found VWF to be elevated but …

… Clark WF, Stewart AK, Rock GA, et al. Plasma exchange when myeloma presents as acute
… Clark WF, Stewart AK, Rock GA, et al. Plasma exchange when myeloma presents as acute …

Objective: To determine the incidence and timing of relapses in patients who have recovered
from an acute episode of thrombotic thrombocytopenic purpura. Design: Clinical follow-up …

OBJECTIVE: The objective of this study was to determine the changes in activated protein C
resistance that occur during normal pregnancy. STUDY DESIGN: In this cross-sectional …

Despite the favourable response of thrombotic thrombocytopenic purpura/haemolytic
uraemic syndrome (TTP/HUS) to plasma exchange, an early level of mortality persists. Non‐…

ContextUse of experimental therapies during but outside of randomized controlled trials (RCTs)
has not been studied.ObjectiveTo determine whether initiation of an RCT leads to …

The Factor VIII procoagulant activity in plasma, cryoprecipitate, and their polyethylene glycol
(PEG) precipitates is markedly increased if blood is collected into heparin rather than into …