The term “frailty” is used loosely to describe a range of conditions in older people, including
general debility and cognitive impairment. There is no clear consensus on the definition of …

Background: There has been concern about under-representation of older people in clinical
trials. The PREDICT study reported that older people and those with co-morbidity continue …

Objective Rheumatoid arthritis (RA) is classically thought of as a Th1, T lymphocyte–driven
disease of the adaptive immune system. However, cells of the innate immune system, …

Background and Purpose— Pneumonia is a major cause of mortality and morbidity in
patients with stroke fed via nasogastric tubes and may be because of vomiting and gastro-…

Introduction Post-stroke hypoxia is common, and may adversely affect outcome. We have
recently shown that oxygen supplementation may improve early neurological recovery. Here, …

Mild hypoxia is common after stroke and associated with poor long-term outcome. Oxygen
supplementation could prevent hypoxia and improve recovery. A previous study of routine …

Acute Ischemic Stroke (AIS) is the major type of stroke occurring in patients. Aspiration
thrombectomy, which uses suction to remove the thrombosis, is a promising technique in the …

… Peter Crome and Frank Lally … No competing interests were declared by Frank Lally. …

Background Mechanical thrombectomy with stent retriever devices is associated with
significantly better outcomes than thrombolysis alone in the treatment of acute ischemic stroke. …

It is perhaps inevitable that every specialty within medicine believes that its fundamental
principles should be included in the core undergraduate curriculum and should be …