Background: We established a program of research to improve the development, reporting
and evaluation of practice guidelines. We assessed the construct validity of the items and user…

• The instrument successfully differentiates between highand low-quality guideline content. 7•
The new user’s manual is well received by users. 7• Users provided considerable …

Background: We undertook research to improve the AGREE instrument, a tool used to evaluate
guidelines. We tested a new seven-point scale, evaluated the usefulness of the original …

Background. Despite clinical guidelines penetrating every aspect of clinical practice and
health policy, doubts persist over their ability to improve patient care. We have designed and …

Objectives: To develop a methodology for evaluating the impact of research on health care,
and to characterise the papers cited on clinical guidelines. Design: The bibliographic details …

Objectives: To identify predictors of high-quality clinical practice guidelines.Methods: A total
of 86 guidelines from 11 countries were assessed by four independent appraisers per …

Importance Clinical practice guidelines (CPGs) may lack rigor and suitability to the setting in
which they are to be applied. Methods to yield clinical practice guideline recommendations …

OBJECTIVE: To explore the role of a four-item Global Rating Scale (GRS) that could be
used in place of the Appraisal of Guidelines, Research and Evaluation II (AGREE II). STUDY …

Objective. Clinical practice guidelines are widely used as effective tools for improving the
management of patients with cancer. However, there is increasing concern about variation in …

India is at crossroads with a commitment by the government to universal health coverage (UHC),
driving efficiency and tackling waste across the public healthcare sector. Health …