This generally well-conducted review concluded that there was no benefit of epidural
analgesia on mortality or length of intensive care unit stay and hospital stay, but there may be a …

Background The effect of a restrictive versus liberal red-cell transfusion strategy on clinical
outcomes in patients undergoing cardiac surgery remains unclear. Methods In this multicenter…

Background: The role of remdesivir in the treatment of patients in hospital with COVID-19
remains ill defined in a global context. The World Health Organization Solidarity randomized …

Background We reported previously that, in patients undergoing cardiac surgery who were at
moderate-to-high risk for death, a restrictive transfusion strategy was noninferior to a liberal …

Importance The surgeon-anesthesiologist teamwork and relationship is crucial to good patient
outcomes. Familiarity among work team members is associated with enhanced success in …

Objective: To examine the association of between hospital rates of high-volume anesthesiology
care and of postoperative major morbidity. Background: Individual anesthesiology …

Background Elevated proinflammatory cytokines are associated with greater COVID-19 severity.
We aimed to assess safety and efficacy of sarilumab, an interleukin-6 receptor inhibitor, …

… Author contributions François Martin Carrier and Michaël Chassé contributed to all
aspects of this manuscript, including study conception and design; acquisition, analysis, and …

Background: The role of remdesivir in the treatment of hospitalized patients with COVID-19
remains ill-defined. We conducted a cost-effectiveness analysis alongside the Canadian …

Background A strategy of administering a transfusion only when the hemoglobin level falls
below 7 or 8 g per deciliter has been widely adopted. However, patients with acute …