The effect on the fetus of spontaneous and induced maternal hyperventilation has been
assessed in 58 patients. A decrease in maternal pCO 2 was accompanied by a corresponding …

This study was designed to investigate the effects of naloxone on athletic performance in
humans. Two groups of elite middle-distance runners performed a maximal or a submaximal …

Clonidine, an alpha 2 adrenergic agonist, has analgesic properties and recently has been
used to suppress opiate withdrawal. These two properties theoretically make it a suitable …

In the rat, the continuous intrathecal (it) infusion of clonidine (0.4 μg/hr) significantly increased
the tail-flick latency (TF) and the threshold for paw pressure (PP) withdrawal for 5 days and …

… Milne and FW Cervenko, 1987a, Determination of cross tolerance in rat spinal cord using …
Milne and FW Cervenko, 1987b, A study of the interaction between clonidine and morphine on …

Continuous intrathecal (IT) infusion via ALZET ® mini-osmotic pumps was used to induce
spinal tolerance to morphine in the rat. Naloxone (1 mg/kg IP), injected on day 3 of continuous …

Mice of two strains, Crl:CD-l(lCR)Br and C57BL6, were exposed to nitrous oxide at
concentrations of 50,65 and 80 per cent for 34 or 68 hours. Cessation of nitrous oxide resulted in …

Ten studies were performed to examine the time course of arterial and venous thiopenlal
concentrations following the administration of thiopental (4mg.kg -1 over 3 min) for cerebral …

Isoflurane (1.5 to 3.0 vol% in oxygen) was used to control intraoperative hypertension in 10
patients undergoing hypothermic cardiopulmonary bypass surgery. Isoflurane was …

The acute intrathecal (it) administration of 10, 25, 50, and 100 μg morphine and 7.5, 10, 15,
and 30 μg (−)norepinephrine (NE) to the rat produced dose-dependent, long-lasting …