[HTML][HTML] Phytochemicals targeting estrogen receptors: beneficial rather than adverse effects?

S Lecomte, F Demay, F Ferrière, F Pakdel - International Journal of …, 2017 - mdpi.com
… Sylvain Lecomte, François Ferrière and Florence Demay were the major contributors in
writing the manuscript. Sylvain Lecomte, Florence Demay, François Ferrière and Farzad Pakdel …

Cyclical DNA methylation of a transcriptionally active promoter

…, F Demay, G Reid, V Benes, A Jeltsch, F Gannon… - Nature, 2008 - nature.com
Processes that regulate gene transcription are directly under the influence of the genome
organization. The epigenome contains additional information that is not brought by DNA …

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

AA Sérandour, S Avner, F Percevault, F Demay… - Genome …, 2011 - genome.cshlp.org
Transcription factors (TFs) bind specifically to discrete regions of mammalian genomes called
cis-regulatory elements. Among those are enhancers, which play key roles in regulation of …

[HTML][HTML] Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections

T Beneke, F Demay, E Hookway, N Ashman… - PLoS …, 2019 - journals.plos.org
… I ) and on the Y-axis the log2 fold change of the spectral index (F S +C S / F I +C I ). To allow
plotting of proteins that were only detected in one fraction, a value of 10 −10 was inserted for …

Synthesis and evaluation of 1, 3, 4-oxadiazole derivatives for development as broad-spectrum antibiotics

…, RG Von Borowski, M Thepaut, HH Le, F Demay… - Bioorganic & medicinal …, 2019 - Elsevier
The reality and intensity of antibiotic resistance in pathogenic bacteria calls for the rapid
development of new antimicrobial drugs. In bacteria, trans-translation is the primary quality …

[HTML][HTML] Deciphering the molecular mechanisms sustaining the estrogenic activity of the two major dietary compounds zearalenone and apigenin in ER-positive breast …

…, F Demay, TH Pham, S Moulis, T Efstathiou, F Chalmel… - Nutrients, 2019 - mdpi.com
The flavone apigenin and the mycotoxin zearalenone are two major compounds found in
the human diet which bind estrogen receptors (ERs), and therefore influence ER activity. …

The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational …

G Flouriot, G Huet, F Demay, F Pakdel… - Biochemical …, 2014 - portlandpress.com
… Guillaume Huet and Florence Demay performed and analysed experiments. Denis Michel
contributed to the data analysis and the writing of the paper with ideas and comments from …

Dynamics of estrogen receptor-mediated transcriptional activation of responsive genes in vivo: apprehending transcription in four dimensions

…, G Reid, G Penot, F Demay, F Gannon… - Hormonal …, 2008 - Springer
Estrogens, such as 17bHestradiol (E2), are commonly recognized as pivotal hormones
controlling female reproductive physiology (1), but they also exhibit pleiotropic actions in male …

T‐box factors: targeting to chromatin and interaction with the histone H3 N‐terminal tail

F Demay, B Bilican, M Rodriguez… - Pigment cell …, 2007 - Wiley Online Library
T‐box transcription factors play a crucial role in development where they are implicated in
patterning and cell fate decisions. Tbx2 and Tbx3 have also been implicated in several …

Steroid-independent activation of ER by GnRH in gonadotrope pituitary cells

F Demay, M De Monti, C Tiffoche, C Vaillant… - …, 2001 - academic.oup.com
In the rat pituitary gland the mechanism responsible for ERα regulation has not been fully
elucidated. Using transient transfection assays in αT3–1 cells, a cell line of gonadotrope origin, …