Background Gabapentinoid drugs (gabapentin and pregabalin) are effective in neuropathic
pain, which has a prevalence of ∼7%. Concerns about increased prescribing have …

… Declaration of funding interests: This systematic review was undertaken as part of the
Kuck Clinical Research Training Fellowship awarded to Dr Emma Fletcher by Research Into …

Adiponectin (APN), an adipokine, exerts an anti-inflammatory and anti-cancerous activity with
its role in glucose and lipid metabolism and its absence related to several obesity related …

Sequences that form DNA secondary structures, such as G‐quadruplexes (G4s) and
intercalated‐Motifs (iMs), are abundant in the human genome and play various physiological roles. …

Background Inflammatory bowel diseases are associated with increased adiponectin (APN)
levels, which may exert pro-inflammatory effects in these individuals. Since habitual …

Maintenance of skeletal muscle mass and function is an incredibly nuanced balance of
anabolism and catabolism that can become distorted within different pathological conditions. In …

Previous studies have shown that chronic heavy alcohol consumption and consumption of a
high-fat (HF) diet can independently contribute to skeletal muscle oxidative stress and …

Background: A systematic review was conducted to determine the impact of Hepatitis C (HCV)
treatment on substance use behaviour in people who inject drugs (PWID). Methods: A …

Background Alcoholic liver disease ( ALD ) is a significant threat to public health and a
leading cause of death. Despite this, the long‐term clinical course and predictive factors of …

Previous studies have demonstrated that circulating microRNA (miR)-210 levels are elevated
in peripheral artery disease (PAD) patients. MiR-210 is known to be a negative regulator of …