When leukocytes are exposed to mitogens or antigens in vitro, they release bone-resorbing
activity into the culture supernatants which can be detected by bioassay 1,2 . Like many …

Structural equation modeling (SEM) has become a mainstream method in many fields of
business research, but its use in family business research remains in its infancy. This lag in …

Huntington's disease (HD) is an inherited, progressive neurological disorder that is caused
by a CAG/polyglutamine repeat expansion and for which there is no effective therapy. Recent …

The androgen receptor (AR) is a key regulator of prostate growth and the principal drug
target for the treatment of prostate cancer. Previous studies have mapped AR targets and …

A low molecular weight serine protease inhibitor (TAP) was purified from extracts of the soft
tick, Ornithodoros moubata. The peptide is a slow, tight-binding inhibitor, specific for factor Xa …

Huntington disease (HD) is a devastating, late-onset, inherited neurodegenerative disorder
that manifests with personality changes, movement disorders, and cognitive decline. It is …

The application of fragment-based screening techniques to cyclin dependent kinase 2 (CDK2)
identified multiple (>30) efficient, synthetically tractable small molecule hits for further …

The manipulation of chaperone levels has been shown to inhibit aggregation and/or rescue
cell death in Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster …

Huntington’s disease (HD), an incurable neurodegenerative disorder, has a complex
pathogenesis including protein aggregation and the dysregulation of neuronal transcription and …

wagner jij, cummings g., smith dl, olson j., anderson l. & warren s. (2010) Journal of Nursing
Management18, 448–462 The relationship between structural empowerment and …