Turner syndrome is suspected in females with short stature, gonadal dysgenesis, and
lymphedema; however, there are no pathognomonic features of Turner syndrome, and the …

Women with a mutation in BRCA1 or BRCA2 face a lifetime risk of breast cancer of approximately
80 %. Tamoxifen treatment of the first cancer has been associated with a reduction in …

Background: To evaluate the effect of the cumulative number of ovulatory cycles and its
contributing components on the risk of breast cancer among BRCA mutation carriers. Methods: …

In May 2014, Evans et al1 reported that children with Down syndrome had lower rates of in-hospital
death after cardiac surgery, compared with children without Down syndrome. Forty …

In order to assess the levels of distress and psychosocial support needs of a high risk population,
we undertook a study to look at both the objective and subjective levels of distress and …

MANY GENETIC DISORDERS DO NOT MANIFEST themselves until the adult years. Such
disorders often involve multiple genetic factors interacting with multiple environmental factors, …

A family with two sisters and their mother's male cousin had ependymomas. Of note is the
fact that chromosome analysis on the tumour of the younger sister showed two cell lines …

By the Berlin criteria (Beighton et al. 1988), the diagnosis of Marfan syndrome can be made
in an individual if there is a positive family history and involvement of at least two systems …

Introduction Ezetimibe (EZ) is a selective cholesterol absorption inhibitor approved for use
in Canada. The effect and tolerability of EZ among patients was evaluated in the clinical …

A 26-year-old woman had a life-threatening attack of status asthmaticus at 12.5 weeks of
pregnancy. Subsequently, an apparently normal male infant was born at full-term.