Purpose : The purpose of this guideline is to provide a clinical framework for the diagnosis,
prevention and follow-up of adult patients with kidney stones based on the best available …

The importin α/β heterodimer targets hundreds of proteins to the nuclear-pore complex (NPC)
and facilitates their translocation across the nuclear envelope. Importin α binds to classical …

ContextHigh plasma homocysteine levels are a risk factor for mortality and vascular disease
in observational studies of patients with chronic kidney disease. Folic acid and B vitamins …

The nuclear envelope defines a compartment boundary which is penetrated by pores that
mediate a remarkable transport process. Precursor RNAs are retained in the nucleus, while …

Nucleus-vacuole (NV) junctions in Saccharomyces cerevisiae are formed through specific
interactions between Vac8p on the vacuole membrane and Nvj1p in the nuclear envelope. …

Translocation through nuclear pore complexes (NPCs) requires interactions between
receptor–cargo complexes and phenylalanine-glycine (FG) repeats in multiple FG domain-…

Vac8p is a vacuolar membrane protein that is required for efficient vacuole inheritance and
fusion, cytosol-to-vacuole targeting, and sporulation. By analogy to other armadillo domain …

Mammalian species have co-evolved with intestinal microbial communities that can shape
development and adapt to environmental changes, including antibiotic perturbation or …

A twin study of genetic and dietary influences on nephrolithiasis: A report from the Vietnam
Era Twin (VET) Registry. Background Nephrolithiasis is a complex phenotype that is …

Background Several studies have suggested that if recombinant human erythropoietin (epoetin)
is administered subcutaneously rather than intravenously, a lower dose may be …