Needle exchange is not enough: lessons from the Vancouver injecting drug use study

SA Strathdee, DM Patrick, SL Currie, PGA Cornelisse… - Aids, 1997 - journals.lww.com
Objective: To describe prevalence and incidence of HIV-1, hepatitis C virus (HCV) and risk
behaviours in a prospective cohort of injecting drug users (IDU). Setting: Vancouver, which …

[PDF][PDF] Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21

ME Hatley, DM Patrick, MR Garcia, JA Richardson… - Cancer cell, 2010 - cell.com
Lung cancer is the leading cause of cancer-related deaths in the world, and non-small-cell
lung cancer (NSCLC) accounts for 80% of cases. MicroRNA-21 (miR-21) expression is …

The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

…, LH Lehmann, DM Patrick… - Proceedings of the …, 2009 - National Acad Sciences
Acute and chronic injuries to the heart result in perturbation of intracellular calcium signaling,
which leads to pathological cardiac hypertrophy and remodeling. Calcium/calmodulin-…

[HTML][HTML] Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

DM Patrick, RL Montgomery, X Qi… - The Journal of …, 2010 - Am Soc Clin Investig
MicroRNAs inhibit mRNA translation or promote mRNA degradation by binding complementary
sequences in 3′ untranslated regions of target mRNAs. MicroRNA-21 (miR-21) is …

Rats, cities, people, and pathogens: a systematic review and narrative synthesis of literature regarding the ecology of rat-associated zoonoses in urban centers

…, KL Parsons, C Jardine, DM Patrick - Vector-Borne and …, 2013 - liebertpub.com
Urban Norway and black rats (Rattus norvegicus and Rattus rattus) are the source of a number
of pathogens responsible for significant human morbidity and mortality in cities around …

Antibiotic use in children is associated with increased risk of asthma

…, K Richardson, LD Lynd, A Kozyrskyj, DM Patrick… - …, 2009 - publications.aap.org
BACKGROUND. Antibiotic exposure in early childhood is a possible contributor to the increasing
asthma prevalence in industrialized countries. Although a number of published studies …

[HTML][HTML] Association between the 2008–09 seasonal influenza vaccine and pandemic H1N1 illness during spring–summer 2009: four observational studies from …

…, G Boivin, JL Gardy, Y Li, TL Kwindt, DM Patrick… - PLoS …, 2010 - journals.plos.org
Background In late spring 2009, concern was raised in Canada that prior vaccination with the
2008–09 trivalent inactivated influenza vaccine (TIV) was associated with increased risk of …

[HTML][HTML] Metagenomics for pathogen detection in public health

RR Miller, V Montoya, JL Gardy, DM Patrick, P Tang - Genome medicine, 2013 - Springer
Traditional pathogen detection methods in public health infectious disease surveillance rely
upon the identification of agents that are already known to be associated with a particular …

[HTML][HTML] A population-based evaluation of a publicly funded, school-based HPV vaccine program in British Columbia, Canada: parental factors associated with HPV …

…, S Dobson, D Money, DM Patrick, M Naus - PLoS …, 2010 - journals.plos.org
Background Information on factors that influence parental decisions for actual human
papillomavirus (HPV) vaccine receipt in publicly funded, school-based HPV vaccine programs for …

Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies

DM Patrick, H Sbihi, DLY Dai, A Al Mamun… - The Lancet …, 2020 - thelancet.com
Background Childhood asthma incidence is decreasing in some parts of Europe and North
America. Antibiotic use in infancy has been associated with increased asthma risk. In the …