Acute inflammation is a protective reaction by the immune system in response to invading
pathogens or tissue damage. Ideally, the response should be localized, self-limited, and …

A substantial and increasing body of clinical evidence supports the role of specific strains and
mixtures of probiotics in the prevention and treatment of certain diseases. Several general …

The primate brain was thought to contain only the GnRH known as mammalian GnRH (mGnRH).
This study investigates whether a second form of GnRH exists within the primate brain. …

Background: Although cardiovascular disease may be partially preventable through dietary
and lifestyle-based interventions, few individuals at risk receive intensive dietary and lifestyle …

Bioregulatory systems medicine (BrSM) is a paradigm that aims to advance current medical
practices. The basic scientific and clinical tenets of this approach embrace an interconnected …

Background Modifying the acute inflammatory response has wide clinical benefits. Current
options include non-steroidal anti-inflammatory drugs (NSAIDs) and therapies that may …

Publisher Summary This chapter discusses the molecular evolution of growth hormone-releasing
hormone (GHRH) and gonadotropin-releasing hormone (GnRH). The mechanism by …

Lipid mediators are important regulators in inflammatory responses, and their biosynthetic
pathways are targeted by commonly used anti-inflammatory drugs. Switching from pro-…

Complex diseases are inherently multifaceted, and the associated data are often heterogeneous,
making linking interactions across genes, metabolites, RNA, proteins, cellular functions…

To better understand the evolution of pituitary adenylate cyclase-activating polypeptide (PACAP)
and growth hormone-releasing hormone (GHRH), we isolated the cDNAs encoding …