Likelihood ratios with confidence: sample size estimation for diagnostic test studies
DL Simel, GP Samsa, DB Matchar - Journal of clinical epidemiology, 1991 - Elsevier
Confidence intervals are important summary measures that provide useful information from
clinical investigations, especially when comparing data from different populations or sites. …
clinical investigations, especially when comparing data from different populations or sites. …
Does this woman have an acute uncomplicated urinary tract infection?
ContextSymptoms suggestive of acute urinary tract infection (UTI) constitute one of the most
common reasons for women to visit clinicians. Although the clinical encounter typically …
common reasons for women to visit clinicians. Although the clinical encounter typically …
Is this patient hypovolemic?
S McGee, WB Abernethy III, DL Simel - Jama, 1999 - jamanetwork.com
ObjectiveTo review, systematically, the physical diagnosis of hypovolemia in adults.MethodsWe
searched MEDLINE (January 1966-November 1997), personal files, and bibliographies …
searched MEDLINE (January 1966-November 1997), personal files, and bibliographies …
Does this patient have delirium?: value of bedside instruments
Context Delirium occurs in many hospitalized older patients and has serious consequences
including increased risk for death and admission to long-term care. Despite its importance, …
including increased risk for death and admission to long-term care. Despite its importance, …
Is this patient having a myocardial infarction?
AA Panju, BR Hemmelgarn, GH Guyatt, DL Simel - Jama, 1998 - jamanetwork.com
When faced with a patient with acute chest pain, clinicians must distinguish myocardial
infarction (MI) from all other causes of acute chest pain. If MI is suspected, current therapeutic …
infarction (MI) from all other causes of acute chest pain. If MI is suspected, current therapeutic …
Does this patient have influenza?
SA Call, MA Vollenweider, CA Hornung, DL Simel… - Jama, 2005 - jamanetwork.com
ContextInfluenza vaccination lowers, but does not eliminate, the risk of influenza. Making a
reliable, rapid clinical diagnosis is essential to appropriate patient management that may be …
reliable, rapid clinical diagnosis is essential to appropriate patient management that may be …
Does the clinical examination predict lower extremity peripheral arterial disease?
NA Khan, SA Rahim, SS Anand, DL Simel, A Panju - Jama, 2006 - jamanetwork.com
ContextLower extremity peripheral arterial disease (PAD) is common and associated with
significant increases in morbidity and mortality. Physicians typically depend on the clinical …
significant increases in morbidity and mortality. Physicians typically depend on the clinical …
Does this patient have a torn meniscus or ligament of the knee?: value of the physical examination
ContextWhile most meniscal or ligamentous knee injuries heal with nonoperative treatments,
a subset should be treated with arthroscopic or open surgery.ObjectiveTo analyze the …
a subset should be treated with arthroscopic or open surgery.ObjectiveTo analyze the …
Is this patient having a stroke?
LB Goldstein, DL Simel - Jama, 2005 - jamanetwork.com
ContextPatients suspected of having a stroke or transient ischemic attack require accurate
assessment for appropriate acute treatment and use of secondary preventive interventions.…
assessment for appropriate acute treatment and use of secondary preventive interventions.…
Does this patient have obstructive sleep apnea?: The Rational Clinical Examination systematic review
KA Myers, M Mrkobrada, DL Simel - Jama, 2013 - jamanetwork.com
Importance Obstructive sleep apnea is a common disease, responsible for daytime sleepiness.
Prior to referring patients for definitive testing, the likelihood of obstructive sleep apnea …
Prior to referring patients for definitive testing, the likelihood of obstructive sleep apnea …