Prolongation and quality of life for HIV-infected adults treated with highly active antiretroviral therapy (HAART): a balancing act

RW Burgoyne, DHS Tan - Journal of antimicrobial …, 2008 - academic.oup.com
Advances in highly active antiretroviral therapy (HAART) options for people living with HIV/AIDS
have resulted in decreased morbidity and mortality. To some extent, the role of disease …

Mpox in people with advanced HIV infection: a global case series

…, AF Costa, SQ Rocha, JV Madruga, DHS Tan… - The Lancet, 2023 - thelancet.com
Background People living with HIV have accounted for 38–50% of those affected in the 2022
multicountry mpox outbreak. Most reported cases were in people who had high CD4 cell …

Peginterferon lambda for the treatment of outpatients with COVID-19: a phase 2, placebo-controlled randomised trial

…, J Powis, J McCready, DHS Tan… - The Lancet …, 2021 - thelancet.com
Background To date, only monoclonal antibodies have been shown to be effective for
outpatients with COVID-19. Interferon lambda-1 is a type III interferon involved in innate antiviral …

[HTML][HTML] Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial

…, A Singh, W Sligl, S Smith, R Somayaji, DHS Tan… - Cmaj, 2022 - Can Med Assoc
Background: The role of remdesivir in the treatment of patients in hospital with COVID-19
remains ill defined in a global context. The World Health Organization Solidarity randomized …

A systematic review of the impacts of oral tetracycline class antibiotics on antimicrobial resistance in normal human flora

…, V Tang, T Grennan, DHS Tan - JAC-antimicrobial …, 2022 - academic.oup.com
Objectives There is interest in doxycycline as prophylaxis against sexually transmitted
infections (STIs), but concern about antimicrobial resistance (AMR). We conducted a systematic …

Pre-exposure prophylaxis for sexually-acquired HIV risk management: a review

…, H Senn, M Sharma, DHS Tan - HIV/AIDS-Research and …, 2015 - Taylor & Francis
Despite significant efforts, the rate of new HIV infections worldwide remains unacceptably
high, highlighting the need for new HIV prevention strategies. HIV pre-exposure prophylaxis (…

[HTML][HTML] Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis

DHS Tan, MW Hull, D Yoong, C Tremblay, P O'byrne… - Cmaj, 2017 - Can Med Assoc
Darrell Tan and Mark Hull wrote the first draft of the synopsis. All of the authors revised the
manuscript critically for important intellectual content, gave final approval of the version to be …

Long-acting cabotegravir plus rilpivirine for treatment in adults with HIV-1 infection: 96-week results of the randomised, open-label, phase 3 FLAIR study

…, O Degen, JG García, EB Morell, DHS Tan… - The Lancet …, 2021 - thelancet.com
Background There is a need for more convenient, less frequent treatment to help address
challenges associated with daily oral HIV treatment in people living with HIV, including stigma, …

Initiation of long-acting cabotegravir plus rilpivirine as direct-to-injection or with an oral lead-in in adults with HIV-1 infection: week 124 results of the open-label phase …

C Orkin, EB Morell, DHS Tan, H Katner… - The Lancet …, 2021 - thelancet.com
Background Previous work established non-inferiority of switching participants who were
virologically suppressed from daily oral standard of care to monthly long-acting intramuscular …

The pre-exposure prophylaxis-stigma paradox: learning from Canada's first wave of PrEP users

…, P MacPherson, MJP Strang, DHS Tan - AIDS patient care and …, 2018 - liebertpub.com
With the emergence of daily oral tenofovir disoproxil fumarate and emtricitabine-based pre-exposure
prophylaxis (PrEP) use in Canada, questions have emerged concerning the …