… Needham has received grant support from the National Institutes of Health. Dr. Bienvenu …
Needham DM: Mobilizing patients in the intensive care unit: Improving neuromuscular …

Clinical research is necessary for an effective response to an emerging infectious disease
outbreak. However, research efforts are often hastily organised and done using various …

Objectives: As critical care advances and intensive care unit mortality declines, the number
of survivors of critical illness is increasing. These survivors frequently experience long-lasting …

Background Catheter-related bloodstream infections occurring in the intensive care unit (ICU)
are common, costly, and potentially lethal. Methods We conducted a collaborative cohort …

Micropipette pressurization of giant bilayer vesicles was used to measure both elastic
bending k c and area stretch K A moduli of fluid-phase phosphatidylcholine (PC) membranes. …

Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:

Microbial community analysis via high‐throughput sequencing of amplified 16S rRNA genes
is an essential microbiology tool. We found the popular primer pair 515F ( 515F‐C ) and …

… Tim Needham Tim Needham received his B.Sc. degree in geology from Imperial College,
London (1981) and a Ph… D. He taught structural geology at the University of Newcastle-upon-Tyne …

Giant bilayer vesicles were reconstituted from several lipids and lipid/cholesterol (CHOL)
mixtures: stearolyloleoylphosphatidylcholine (SOPC), bovine sphingomyelin (BSM), …

The single biggest challenge now facing drug delivery (for liposomes and indeed other carriers)
is to initiate and produce release of the encapsulated drug only at the diseased site and …