User profiles for D. M. Wilson

David Matthew Wilson

VP & Head, Discovery Chemistry Europe, Janssen Pharmaceuticals
Verified email at astrazeneca.com
Cited by 10144

The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population‐based cohort: the Rochester Diabetic …

…, JL Karnes, WJ Litchy, R Klein, JM Pach, DM Wilson… - Neurology, 1993 - AAN Enterprises
… This report provides an improved estimate of the frequency of diabetes mellitus and its
complications in the community. Our estimate of the prevalence of diabetes mellitus is lower and …

[PDF][PDF] Hallmarks of neurodegenerative diseases

DM Wilson, MR Cookson, L Van Den Bosch… - Cell, 2023 - cell.com
Decades of research have identified genetic factors and biochemical pathways involved in
neurodegenerative diseases (NDDs). We present evidence for the following eight hallmarks …

The WASP project and the SuperWASP cameras

…, B Smalley, PJ Wheatley, DM Wilson - Publications of the …, 2006 - iopscience.iop.org
The SuperWASP cameras are wide‐field imaging systems at the Observatorio del Roque
de los Muchachos on the island of La Palma in the Canary Islands, and at the Sutherland …

[HTML][HTML] Rituximab, B-lymphocyte depletion, and preservation of beta-cell function

…, DA Schatz, D Wherrett, DM Wilson… - … England Journal of …, 2009 - Mass Medical Soc
Background The immunopathogenesis of type 1 diabetes mellitus is associated with T-lymphocyte
autoimmunity. However, there is growing evidence that B lymphocytes play a role in …

Reexamining the empirical evidence for an environmental Kuznets curve

WT Harbaugh, A Levinson, DM Wilson - Review of Economics and …, 2002 - direct.mit.edu
This paper uses an updated and revised panel data set on ambient air pollution in cities
worldwide to examine the robustness of the evidence for the existence of an inverted U-shaped …

Organic synthesis provides opportunities to transform drug discovery

…, I Churcher, DC Rees, AW Thomas, DM Wilson… - Nature …, 2018 - nature.com
Despite decades of ground-breaking research in academia, organic synthesis is still a rate-limiting
factor in drug-discovery projects. Here we present some current challenges in …

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

…, G Drewes, U Oppermann, DJ Patel, K Lee, DM Wilson - Nature, 2012 - nature.com
The jumonji (JMJ) family of histone demethylases are Fe 2+ - and α-ketoglutarate-dependent
oxygenases that are essential components of regulatory transcriptional chromatin …

Weight concerns influence the development of eating disorders: a 4-year prospective study.

…, C Hayward, KF Haydel, DM Wilson… - Journal of consulting …, 1996 - psycnet.apa.org
The authors examined factors prospectively associated with age of onset of partial syndrome
eating disorders over a 4-year interval in a community sample (n= 877) of high school-age …

Pursuit of thinness and onset of eating disorder symptoms in a community sample of adolescent girls: A three‐year prospective analysis

…, CB Taylor, C Hayward, DM Wilson… - … Journal of Eating …, 1994 - Wiley Online Library
Community‐based prospective studies are needed to shed light on mechanisms that may
influence development of eating disorders and identify variables that could serve as potential …

The central nervous control of flight in a locust

DM Wilson - Journal of Experimental Biology, 1961 - journals.biologists.com
… allowed for conduction, the record indicates firing of the sensory unit mostly just before activity
in the basalar muscle which fires 2− 3 msec, before the top position (Weis-Fogh & Wilson). …