User profiles for D. Levasseur

Dana Levasseur

Beam Therapeutics
Verified email at beamtx.com
Cited by 5262

Pedagogy meets PowerPoint: A research review of the effects of computer-generated slides in the classroom

DG Levasseur, J Kanan Sawyer - The Review of Communication, 2006 - Taylor & Francis
The present essay offers a comprehensive review of the effects of computer-generated slides
in the classroom, beginning with an overview of the ongoing debate over whether. To date, …

[HTML][HTML] A comparative encyclopedia of DNA elements in the mouse genome

…, R Samstein, EE Eichler, SH Orkin, D Levasseur… - Nature, 2014 - nature.com
The laboratory mouse shares the majority of its protein-coding genes with humans, making
it the premier model organism in biomedical research, yet the two mammals differ in …

A protein interaction network for pluripotency of embryonic stem cells

J Wang, S Rao, J Chu, X Shen, DN Levasseur… - Nature, 2006 - nature.com
… (c) and Oct4 (d) in ES cells expressing BirA without (a, b) or with (c, d) bio Nanog. The …
are shown as means and sem from two clones in c and three independent experiments in d. …

The transcriptional network controlling pluripotency in ES cells

…, X Shen, DN Levasseur - Cold Spring Harbor …, 2008 - symposium.cshlp.org
… Heterogeneous nuclear ribonucleoprotein d-like … we identified multiple potential regulatory
elements over more than 160 kb, as reflected by DNase-I-hypersensitive sites (Levasseur et al…

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency

…, M Lawrence, S Dietmann, S Das, DN Levasseur… - Nature, 2013 - nature.com
Molecular control of the pluripotent state is thought to reside in a core circuitry of master
transcription factors including the homeodomain-containing protein NANOG 1 , 2 , which has an …

Correction of a mouse model of sickle cell disease: lentiviral/antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells

DN Levasseur, TM Ryan, KM Pawlik, TM Townes - Blood, 2003 - ashpublications.org
Although sickle cell anemia was the first hereditary disease to be understood at the
molecular level, there is still no adequate long-term treatment. Allogeneic bone marrow …

Requirement of Nanog dimerization for stem cell self-renewal and pluripotency

J Wang, DN Levasseur… - Proceedings of the …, 2008 - National Acad Sciences
Pluripotency of embryonic stem (ES) cells is maintained by transcription factors that form a
highly interconnected protein interaction network surrounding the homeobox protein Nanog. …

[HTML][HTML] Disruption of the BCL11A erythroid enhancer reactivates fetal hemoglobin in erythroid cells of patients with β-thalassemia major

…, Y Zhou, D Dalas, E Yannaki, DN Levasseur… - … Therapy-Methods & …, 2018 - cell.com
In the present report, we carried out clinical-scale editing in adult mobilized CD34+ hematopoietic
stem and progenitor cells (HSPCs) using zinc-finger nuclease-mediated disruption of …

To provide or not to provide course PowerPoint slides? The impact of instructor-provided slides upon student attendance and performance

DL Worthington, DG Levasseur - Computers & Education, 2015 - Elsevier
As PowerPoint has pervaded today's college classrooms, instructors have struggled with
the issue of whether or not to provide students' with copies of course PowerPoint slides (…

Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells

DN Levasseur, J Wang, MO Dorschner… - Genes & …, 2008 - genesdev.cshlp.org
Embryonic stem (ES) cells offer insight into early developmental fate decisions, and their
controlled differentiation may yield vast regenerative potential. The molecular determinants …