The use of total parenteral nutrition (TPN), in the critically ill, may be associated with the
translocation of bacteria and their products from the lumen of the gastrointestinal tract (GIT) to …

Study objective To quantify simultaneously the pulmonary and gastrointestinal (GI) damage
that occurs during uncomplicated surgery requiring cardiopulmonary bypass (CPB), and to …

Study objective: To establish the natural history of lung injury in adult respiratory distress
syndrome (ARDS) in terms of increased pulmonary vascular permeability. Secondly, to relate …

The most important epidemiological, aetiological and diagnostic problems related to
nosocomial pneumonia in the intensive care unit and its significance are reviewed. Areas of …

… Valberg LS, Sinclair DG, WadeJ: Conceptual framework for the future academic medical …
Sinclair DG: The academic medical center: an idea whose time has come. Can Med Assoc J …

… Sinclair DG, Haslam PL, Quinlan GJ, et al: The effect of cardiopulmonary bypass on
intestinal and pulmonary endothelial permeability. Chest 1995; 108:718-724 … Davies SW …

Dose- and time-response studies were performed in iron-loaded and iron-deficient rats in
order to define, (a) the kinetics of absorption of cobalt and iron, (b) the nature of the inhibitory …

… In this volume, Sinclair, Rochon and Leatt have produced a rich, yet readable rendition of
these two stories. Riding the Third Rail: The Story of Ontario's Health Services Restructuring …

The intravenous injection of Escherichia coli endotoxin (3 mg/kg) into dogs caused an
increase in lymph flow from the thoracic duct. The lymph concentrations of macromolecules (…

Three cases of severe community acquired pneumonia requiring ventilatory support are
presented. Continuous positive airway pressure (CPAP) applied via a tightly fitting face mask …