Life-threatening bronchiolitis related to electronic cigarette use in a Canadian youth

ST Landman, I Dhaliwal, CA Mackenzie, T Martinu… - Cmaj, 2019 - Can Med Assoc
BACKGROUND: Although electronic cigarettes (e-cigarettes) were initially marketed as a
potential smoking-cessation aid and a safer alternative to smoking, the long-term health effect …

[HTML][HTML] Asthma control, airway mucus, and 129Xe MRI ventilation after a single benralizumab dose

…, RL Eddy, S Jeimy, C Licskai, CA Mackenzie… - Chest, 2022 - Elsevier
Background Patients with eosinophilic asthma often report poor symptomatic control and
quality of life. Anti-IL-5 therapy, including anti-IL-5Rα (benralizumab), rapidly depletes …

[HTML][HTML] CT mucus score and 129Xe MRI ventilation defects after 2.5 years' anti-IL-5Rα in eosinophilic asthma

…, H Serajeddini, A Bhalla, C Licskai, CA Mackenzie… - Chest, 2023 - Elsevier
Background We previously showed in patients with poorly controlled eosinophilic asthma
that a single dose of benralizumab resulted in significantly improved Asthma Control …

[HTML][HTML] Acute renal injury cause by confirmed Psilocybe cubensis mushroom ingestion

…, HS Myron, RK Summerbell, CA Mackenzie - Medical mycology case …, 2019 - Elsevier
Psilocybe mushrooms are consumed for their hallucinogenic properties. Fortunately, there
are relatively few adverse effects associated with their consumption. This is the first reported …

Pulmonary functional MRI and CT in a survivor of bronchiolitis and respiratory failure caused by e-cigarette use

…, D Knipping, ST Landman, KJ Bosma, CA Mackenzie… - Chest, 2020 - Elsevier
Although nearly 3,000 e-cigarette-related hospitalizations have been reported in North
America, the long-term outcomes in these patients have not been described. We followed an 18-…

[HTML][HTML] The CRTh2 polymorphism rs533116 G> A associates with asthma severity in older females

N Shrestha Palikhe, CA Mackenzie, C Licskai… - Frontiers in …, 2022 - frontiersin.org
CRTh2 is G protein coupled receptor for prostaglandin D2 (PGD)2 expressed by immune cells
that drive type 2 inflammation such as CD4+ T cells (Th2), eosinophils and group 2 innate …

Cyclosporine as a novel treatment for amatoxin-containing mushroom poisoning: a case series

CA Mackenzie, E Austin, M Thompson… - Toxicology …, 2022 - Taylor & Francis
Ingestion of amatoxin-containing mushrooms can lead to fulminant hepatotoxicity and death.
Despite recent interest in therapeutic options for amatoxin-exposed patients, there is no …

[HTML][HTML] 129Xe MRI and Oscillometry of Irritant-Induced Asthma After Bronchial Thermoplasty

…, HK Kooner, RL Eddy, G Parraga, CA Mackenzie - Chest, 2024 - Elsevier
Irritant-induced asthma (IIA) may develop after acute inhalational exposure in individuals
without preexisting asthma. The effect of bronchial thermoplasty to treat intractable, worsening …

Posterior reversible encephalopathy syndrome following iatrogenic acetylcysteine overdose: a case report

J Jae, Y Li, CA Mackenzie - Toxicology Communications, 2023 - Taylor & Francis
We present a case of posterior reversible encephalopathy syndrome (PRES) linked to N-acetylcysteine
(NAC) overdose during treatment for acetaminophen overdose. The patient …

An association between positive airway pressure device manufacturer and incident cancer? A secondary data analysis

…, A Malhotra, AS Gershon, C Mackenzie… - American Journal of …, 2021 - atsjournals.org
Methods We conducted the current study to assess the relationship between the
manufacturer of PAP therapy devices and incident cancer. We hypothesized that …