Background In the antibiotic era, tuberculosis (TB) still causes a substantial number of
mortalities. We aimed to identify the causes and risks of death among TB patients. Methods …

Abstract Changes in mitochondrial dynamics (fusion and fission) are known to occur during
stem cell differentiation; however, the role of this phenomenon in tissue aging remains …

Patients with chronic kidney disease have increased morbidity and mortality, mainly due to
cardiovascular disease. Compared with the general population, patients with chronic kidney …

MicroRNA-128 (miR-128) is an attractive therapeutic molecule with powerful glioblastoma
regulation properties. However, miR-128 lacks biological stability and leads to poor delivery …

Caffeic acid (CA), a natural phenolic compound, is abundant in medicinal plants. CA possesses
multiple biological effects such as anti-bacterial and anti-cancer growth. CA was also …

… Lin, Chou-Han a,b ; Perger, Elisa c ; Lyons, Owen D. a,d,e … Chen LD, Lin L, Ou YW, et
al. Effect of positive airway pressure on glomerular filtration rate in patients with sleep-disordered …

Sirtuins, NAD + -dependent deacetylases, could target both histones and nonhistone
proteins in mammalian cells. Sirt1 is the major sirtuin and has been shown to involve various …

Plasticizers/phthalates play a facilitating role in the development of cancer and help the
tumor to grow and metastasize. Camptothecin (CPT) and its derivatives are known to have …

Non-small cell lung cancer (NSCLC) is a type of malignant cancer, and 85% of metastatic
NSCLC patients have a poor prognosis. C 2 -ceramide induces G2/M phase arrest and …

Ceramides, abundant sphingolipids on the cell membrane, can act as signaling molecules
to regulate cellular functions including cell viability. Exogenous ceramide has been shown to …