Hematopoietic stem cell transplantation: a primer for the primary care physician

CS Léger, TJ Nevill - Cmaj, 2004 - Can Med Assoc
HEMATOPOIETIC STEM CELL TRANSPLANTATION has been used for many years to treat
various malignant and nonmalignant hematologic conditions. However, the high-dose …

[HTML][HTML] Clinical features, treatment, and outcome of HIV-associated immune thrombocytopenia in the HAART era

KLS Ambler, LM Vickars, CS Leger, LM Foltz… - Advances in …, 2012 - hindawi.com
The characteristics of HIV-associated ITP were documented prior to the HAART era, and the
optimal treatment beyond HAART is unknown. We performed a review of patients with HIV-…

Improved survival in patients with myelodysplastic syndrome receiving iron chelation therapy

HA Leitch, CS Leger, TA Goodman, KK Wong… - Clinical Leukemia, 2008 - Elsevier
Purpose Patients with myelodysplastic syndrome (MDS) and iron overload (IOL) often receive
iron chelation therapy (ICT); however, data on clinical outcomes are limited. We reviewed …

Improved survival in red blood cell transfusion dependent patients with primary myelofibrosis (PMF) receiving iron chelation therapy

…, DHC Wong, M Badawi, CS Leger… - Hematological …, 2010 - Wiley Online Library
Many patients with primary myelofibrosis (PMF) become red blood cell (RBC) transfusion
dependent (TD), risking iron overload (IOL). Iron chelation therapy (ICT) may decrease the risk …

Clinical progression and outcome of patients with monoclonal B-cell lymphocytosis

SS Fung, KL Hillier, CS Leger, I Sandhu… - Leukemia & …, 2007 - Taylor & Francis
Monoclonal B-cell lymphocytosis (MBL) is a clonal lymphoproliferation with the immunophenotype
of chronic lymphocytic leukemia (CLL) but a B-lymphocyte count of less than 5 × 10 9 /…

Improved survival with iron chelation therapy for red blood cell transfusion dependent lower IPSS risk MDS may be more significant in patients with a non-RARS …

HA Leitch, C Chan, CS Leger, LM Foltz, KM Ramadan… - Leukemia research, 2012 - Elsevier
Retrospective analyses suggest iron overload is associated with inferior survival (OS) in
lower risk MDS and iron chelation therapy (ICT) with improvement. However, an analysis of …

Improved survival in patients with myelodysplastic syndrome (MDS) receiving iron chelation therapy.

…, KK Wong, LM Vickars, PF Galbraith, CS Leger - Blood, 2006 - Elsevier
Patients (pts) with MDS and iron overload often receive iron chelation therapy (ICT), although
there are no data demonstrating that this improves clinical outcome. Pts with thalassemia …

Autologous blood and marrow transplantation in patients 60 years and older

CS Leger, C Bredeson, B Kearns… - Biology of Blood and …, 2000 - Elsevier
Although many hematologic malignancies are more common in older patients, autologous
blood and marrow transplantation (ABMT) has traditionally been restricted to patients younger …

Ferrous fumarate-induced malabsorption of thyroxine

CS Leger, TC Ooi - The Endocrinologist, 1999 - journals.lww.com
We present the case of a 60-year-old woman with long-standing primary hypothyroidism,
clinically and biochemically euthyroid on the same dose of thyroxine for years, who became …

[HTML][HTML] Improved Leukemia-Free and Overall Survival in Patients with Myelodysplastic Syndrome Receiving Iron Chelation Therapy: A Subgroup Analysis.

HA Leitch, DHC Wong, CS Leger, KM Ramadan… - Blood, 2007 - Elsevier
Myelodysplastic syndrome (MDS) is characterized by ineffective hematopoiesis and risk of
progression to acute myeloid leukemia (AML). Many MDS patients (pts) require red blood cell …