* These authors contributed equally to this project. Supported by grants from the National
Institutes of Health (AI026322, HL63248, and AI066020) and an award from the Bunning Food …

IL-33, a new member of the IL-1 cytokine family, promotes Th2 inflammation, but evidence
on the implications of this cytokine in asthma is lacking. IL-33 would be mainly expressed by …

Background A previous American College of Chest Physicians Consensus Statement on
asthma in the workplace was published in 1995. The current Consensus Statement updates the …

Background: It is unclear whether asthma is overdiagnosed in developed countries, particularly
among obese individuals, who may be more likely than nonobese people to experience …

Background In patients with severe eosinophilic asthma, local maturation rather than systemic
recruitment of mature cells might contribute to persistent airway eosinophilia. Group 2 …

Importance Although asthma is a chronic disease, the expected rate of spontaneous
remissions of adult asthma and the stability of diagnosis are unknown. Objective To determine …

Background This phase 3 study further characterizes the efficacy and safety of reslizumab (a
humanized anti-IL-5 monoclonal antibody) in patients aged 12 to 75 years with asthma …

BACKGROUND: Airway remodeling in asthma comprises a range of structural changes.
Several studies have suggested an association between these changes and disease severity. …

Occupational asthma has been defined as asthma due to conditions attributable to work
exposures, not to causes outside the workplace. This review focuses on current data on …

BACKGROUND: In 2010, the Canadian Thoracic Society (CTS) published a Consensus
Summary for the diagnosis and management of asthma in children six years of age and older, …