Alzheimer's disease (AD) is a frequent and irreversible age-related neurodegeneration
without efficient treatment. Experimental AD in mice responds positively to decreased insulin-like …

Hypothalamic tanycytes are specialized glial cells lining the third ventricle. They are recently
identified as adult stem and/or progenitor cells, able to self-renew and give rise to new …

Background: We have previously demonstrated that CpG oligodeoxynucleotides (CpG-ODNs)
protect against eosinophilia and airway hyperresponsiveness in murine models of …

OBJECTIVE• To compare the oncological outcomes of active surveillance (AS), radical
nephrectomy (RN) and partial nephrectomy (PN) in the management of T1a small renal …

Seminal studies using post-mortem brains of patients with Alzheimer’s disease evidenced
aberrant insulin-like growth factor 1 receptor (IGF1R) signalling. Addressing causality, work in …

Endotoxin is one of the principal components of grain dust that causes acute reversible
airflow obstruction and airway inflammation. To determine whether endotoxin responsiveness …

Murine models of acute atopic asthma may be inadequate to study the effects of recurrent
exposure to inhaled allergens, such as the epithelial changes seen in asthmatic patients. We …

Research has shown that shiftworkers experience poor sleep and high levels of fatigue.
Although considerable research has been performed on fatigue within many shift-work …

Consumption of isoflavone-rich soyabean protein is reported to reduce total and LDL-cholesterol,
but the specific components responsible are undetermined. In a previous crossover …

Bronchopulmonary dysplasia in premature infants is characterized by inhibited alveolarization
and vasculogenesis. Our goal was to generate a mouse model of inhibited alveolarization …