User profiles for Candice Brown

Candice M. Brown Ph.D.

Associate Professor of Neuroscience, West Virginia University School of Medicine
Verified email at hsc.wvu.edu
Cited by 3872

[HTML][HTML] Heat stress in older individuals and patients with common chronic diseases

GP Kenny, J Yardley, C Brown, RJ Sigal, O Jay - Cmaj, 2010 - Can Med Assoc
Observational studies have shown that people aged 60 years and older are among the
worst affected by extreme heat, 3− 5 with those living in institutions, confined to bed or living …

APOE genotype-specific differences in the innate immune response

MP Vitek, CM Brown, CA Colton - Neurobiology of aging, 2009 - Elsevier
Apolipoprotein-E protein is an endogenous immunomodulatory agent that affects both the
innate and the adaptive immune responses. Since individuals with the APOE4 gene …

Managing dyspnea in patients with advanced chronic obstructive pulmonary disease: a Canadian Thoracic Society clinical practice guideline

…, I Mayers, V Kennedy, TK Oliver, C Brown… - Canadian respiratory …, 2011 - hindawi.com
Dyspnea is a cardinal symptom of chronic obstructive pulmonary disease (COPD), and its
severity and magnitude increases as the disease progresses, leading to significant disability …

Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions

S Suzuki, CM Brown, CD Dela Cruz… - Proceedings of the …, 2007 - National Acad Sciences
Recent studies describing the seemingly contradictory actions of estrogens in ischemic
stroke injury have led us to reevaluate the circumstances under which estrogen therapy (ET) …

Neuroprotective effects of estrogens following ischemic stroke

S Suzuki, CM Brown, PM Wise - Frontiers in neuroendocrinology, 2009 - Elsevier
Our laboratory has investigated whether and how 17β-estradiol (E 2 ) protects the brain against
neurodegeneration associated with cerebrovascular stroke. We have discovered that low…

Long-term effects on cognitive function of postmenopausal hormone therapy prescribed to women aged 50 to 55 years

…, I Leng, JAE Manson, CM Brown… - JAMA internal …, 2013 - jamanetwork.com
Importance Postmenopausal hormone therapy with conjugated equine estrogens (CEEs)
may adversely affect older women’s cognitive function. It is not known whether this extends to …

Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease

…, JG Wilson, AL Everhart, CM Brown… - Journal of …, 2015 - Soc Neuroscience
The pathogenesis of Alzheimer9s disease (AD) is a critical unsolved question; and although
recent studies have demonstrated a strong association between altered brain immune …

Effects of Nasal O2 on Sleep-Related Disordered Breathing in Ambulatory Patients with Stable Heart Failure

S Javaheri, M Ahmed, TJ Parker, CR Brown - Sleep, 1999 - academic.oup.com
Objective: The purpose of this study was 1) to determine the effects of nasal O 2 on periodic
breathing, arterial oxyhemoglobin desaturation and nocturnal ventricular arrhythmias in …

Fueling the flame: bioenergy couples metabolism and inflammation

TF Liu, CM Brown, M El Gazzar… - Journal of leukocyte …, 2012 - academic.oup.com
Review on how the integration of bioenergetics and metabolism controls inflammation
progression. We review the emerging concept that changes in cellular bioenergetics …

Production of proinflammatory cytokines and chemokines during neuroinflammation: novel roles for estrogen receptors α and β

CM Brown, TA Mulcahey, NC Filipek, PM Wise - Endocrinology, 2010 - academic.oup.com
… *Address all correspondence and requests for reprints to: Candice M. Brown, Department
of Physiology and Biophysics, University of Washington, Box 356460, Seattle, Washington …