Background: coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome—coronavirus-2 (SARS-CoV-2)—is an ongoing pandemic with high morbidity and …

Transplant patients are at particular risk for developing post‐transplant lymphoproliferative
disease (PTLD) following administration of immunosuppressive therapy. In many cases the …

… APC/C functions. This review integrates the overall functions and properties of the APC/C
with … cryo-electron microscopy (cryo-EM) studies of reconstituted human APC/C complexes. …

Epstein–Barr virus (EBV) has been associated with serious or fatal lymphoproliferative
disease in immunocompromised patients. EBV nuclear protein 2 and latent membrane protein …

… By 36 hr c-myc RNA was transiently induced, and CD21 and CD23 RNAs were beginning
to increase. This coincided with low-level EBNA-1, EBNA-3A, B, and C, and latent membrane …

… 1C,D), but gata4 is expressed in endothelial cells of the valve primordia at E6 (Fig. 1C),
and the fibrous mitral valve leaflets at E10 (Fig. 1D). Myocardial expression of tbx5 is …

… B, Nuclear localization of FOXO1 is restricted to the compact layer (C) by N7 (arrows). C,
Quantification of FOXO1 positive nuclei in ventricular myocardium demonstrates an 82% …

… 94C (“hot start”) to denature the DNA, 1.5 minutes at 55C for primer annealing and I .5 minutes
at 72C … At the end of the last cycle, the samples were incubated at 72C for an additional IO …

… APC/C–MCC complex (APC/C MCC ). Degron-like sequences of the MCC subunit BubR1
block degron recognition sites on Cdc20, the APC/C … to repress APC/C ubiquitination activity. …

… /C Cdc20 rather than APC/C Cdh1 , and interacts with the binding sites of both the C-box
and Ile-Arg tail motifs. Our results reveal the mechanism for the regulation of mitotic APC/C by …