Despite comprising much of the eukaryotic genome, few transposons are active, and they
usually confer no benefit to the host. Through an exaggerated process of genome …

Purpose: Congenital achromatopsia (ACHM) is an autosomal recessive disorder in which
cone function is absent or severely reduced. Gene therapy in animal models of ACHM have …

PURPOSE The National Cancer Institute of Canada-Clinical Trials Group (NCIC-CTG)
conducted a phase II study to assess the efficacy and toxicity of docetaxel as first-line …

Purpose: Congenital achromatopsia is an autosomal recessive disease causing substantial
reduction or complete absence of cone function. Although believed to be a relatively …

… pyriformis and P. tetraurelia GenBank annotations present two different structures for the rns
split: Tetrahymena has a short rns_a followed by a long rns_b, whereas Paramecium has a …

Purpose.: We surveyed inner retinal microscopic features in retinal and neurologic disease
using a reflectance confocal adaptive optics scanning light ophthalmoscope (AOSLO). …

Purpose: To characterize outer retina structure in best vitelliform macular dystrophy (BVMD)
and to determine the effect of macular lesions on overlying and adjacent photoreceptors. …

Ericoid mycorrhizal fungi (ERM) may specialize in capturing nutrients from their host's litter
as a strategy for regulating nutrient cycles in terrestrial ecosystems. In spite of their potential …

Background Programmed DNA elimination and reorganization frequently occur during
cellular differentiation. Development of the somatic macronucleus in some ciliates presents an …

DNA rearrangements, including insertions, deletions, and inversions, control gene expression
in numerous prokaryotic and eukaryotic systems, ranging from phase variation of surface …