User profiles for Brian K. Kwon

Brian K Kwon

UBC
Verified email at ubc.ca
Cited by 23394

Pathophysiology and pharmacologic treatment of acute spinal cord injury

BK Kwon, W Tetzlaff, JN Grauer, J Beiner, AR Vaccaro - The spine journal, 2004 - Elsevier
BACKGROUND CONTEXT: The past three decades have witnessed increasing interest in
strategies to improve neurologic function after spinal cord injury. As progress is made in our …

A systematic review of cellular transplantation therapies for spinal cord injury

…, MD Kawaja, MG Fehlings, BK Kwon - Journal of …, 2011 - liebertpub.com
Cell transplantation therapies have become a major focus in pre-clinical research as a
promising strategy for the treatment of spinal cord injury (SCI). In this article, we systematically …

A clinical practice guideline for the management of patients with degenerative cervical myelopathy: recommendations for patients with mild, moderate, and severe …

…, S Kalsi-Ryan, M Kotter, BK Kwon… - Global spine …, 2017 - journals.sagepub.com
Study Design: Guideline development. Objectives: The objective of this study is to develop
guidelines that outline how to best manage (1) patients with mild, moderate, and severe …

Proposal of a modified, treatment-oriented classification of odontoid fractures

JN Grauer, B Shafi, AS Hilibrand, JS Harrop, BK Kwon… - The Spine Journal, 2005 - Elsevier
BACKGROUND CONTEXT: The classification scheme of odontoid fractures described by
Anderson and D'Alonzo is the one most commonly used. However, uncertainty exists in the …

A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury

…, G Maurais, C Kuntz, CI Shaffrey, BK Kwon… - Journal of …, 2011 - liebertpub.com
Multiple lines of evidence have validated the Rho pathway as important in controlling the
neuronal response to growth inhibitory proteins after central nervous system (CNS) injury. A …

Animal models used in spinal cord regeneration research

BK Kwon, TR Oxland, W Tetzlaff - Spine, 2002 - journals.lww.com
Study Design. A literature review was conducted. Objectives. To review animal models and
injury paradigms used in the neurobiologic study of spinal cord regeneration, and to assist …

Cerebrospinal fluid inflammatory cytokines and biomarkers of injury severity in acute human spinal cord injury

BK Kwon, AMT Stammers, LM Belanger… - Journal of …, 2010 - liebertpub.com
There is an urgent need for both the scientific development and clinical validation of novel
therapies for acute spinal cord injury (SCI). The scientific development of novel therapies …

A clinical practice guideline for the management of acute spinal cord injury: introduction, rationale, and scope

…, LA Tetreault, JR Wilson, BK Kwon… - Global spine …, 2017 - journals.sagepub.com
Acute spinal cord injury (SCI) is a traumatic event that results in disturbances to normal
sensory, motor, or autonomic function and ultimately affects a patient’s physical, psychological, …

Survival and regeneration of rubrospinal neurons 1 year after spinal cord injury

BK Kwon, J Liu, C Messerer… - Proceedings of the …, 2002 - National Acad Sciences
Scientific interest to find a treatment for spinal cord injuries has led to the development of
numerous experimental strategies to promote axonal regeneration across the spinal cord injury …

A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury

BK Kwon, E Okon, J Hillyer, C Mann… - Journal of …, 2011 - liebertpub.com
An increasing number of therapies for spinal cord injury (SCI) are emerging from the laboratory
and seeking translation into human clinical trials. Many of these are administered as …