… Bernie O’Brien. The paper was prepared whilst Elisabeth Fenwick was a postdoctoral fellow
supervised by Bernie O’Brien at … At the time that the paper was written, Bernie O’Brien was …

ContextAlthough advance directives are commonly used in the community, little is known
about the effects of their systematic implementation.ObjectivesTo examine the effect of …

Four different types of evaluation methods, cost‐benefit analysis (CBA), cost‐utility analysis (CUA),
cost‐effectiveness analysis (CEA) and cost‐minimization analysis (CMA), are usually …

Application of techniques such as cost-effectiveness analysis (CEA) is growing rapidly in
health care. There are two general approaches to analysis: deterministic models based upon …

Background Every year in Ontario, the records of over 42 million prescriptions dispensed to
persons eligible for Ontario Drug Benefit (ODB) benefits are transmitted to a central database…

▪ Abstract As many more clinical trials collect economic information within their study design,
so health economics analysts are increasingly working with patient-level data on both costs …

Background The primary aim of this study was to compare quality-of-life outcome between
patients randomized to implantable cardioverter defibrillator (ICD) therapy and patients …

When choosing between mutually exclusive treatment options, it is common to construct a
cost-effectiveness frontier on the cost-effectiveness plane that represents efficient points from …

CLINICAL SCENARIO You are a general internist on the staff of a large community hospital.
Your chief of medicine knows of your interest in evidence-based medicine, and she asks …

BACKGROUND: Data from the Canadian Study of Health and Aging (CSHA) were used to
examine the relation between severity of Alzheimer's disease, as measured by the Mini-…