Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging
…, L Cusan, JL Gomez, B Candas - The Journal of …, 1997 - academic.oup.com
The present data show a dramatic decline in the circulating levels of dehydroepiandrosterone
(DHEA), DHEA-sulfate (DHEA-S), androst-5-ene-3β,17β-diol (5-diol), 5-diol-sulfate, 5-diol-…
(DHEA), DHEA-sulfate (DHEA-S), androst-5-ene-3β,17β-diol (5-diol), 5-diol-sulfate, 5-diol-…
Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology
…, A Bélanger, L Cusan, B Candas - The Journal of Clinical …, 1997 - academic.oup.com
This study analyzes in detail the serum concentration of the active androgens and estrogens,
as well as a series of free and conjugated forms of their precursors and metabolites, after …
as well as a series of free and conjugated forms of their precursors and metabolites, after …
[PDF][PDF] Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women
…, JL Gomez, A Belanger, B Candas - Journal of Clinical …, 1997 - researchgate.net
The effect of 12-month dehydroepiandrosterone (DHEA) replacement therapy has been
evaluated in 14 60-to 70-yr-old women who received daily applications of a 10% DHEA cream. …
evaluated in 14 60-to 70-yr-old women who received daily applications of a 10% DHEA cream. …
Screening decreases prostate cancer death: first analysis of the 1988 Quebec prospective randomized controlled trial
F Labrie, B Candas, A Dupont, L Cusan… - The …, 1999 - Wiley Online Library
BACKGROUND The 46,193 men aged 45 to 80 years registered in the electoral roll of Quebec
City and its Metropolitan area were randomized in November 1988 between screening …
City and its Metropolitan area were randomized in November 1988 between screening …
DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging
…, C Labrie, J Simard, L Cusan, JL Gomez, B Candas - Steroids, 1998 - Elsevier
Human and some other primates are unique since their adrenals secrete large amounts of
dehydroepiandrosterone (DHEA) and its sulfate (DHEA-S), which are converted into …
dehydroepiandrosterone (DHEA) and its sulfate (DHEA-S), which are converted into …
Androgen glucuronides, instead of testosterone, as the new markers of androgenic activity in women
…, C Martel, L Cusan, J Gomez, B Candas… - The Journal of steroid …, 2006 - Elsevier
Despite the long series of cohort studies performed during the last 20 years, the correlation
between serum testosterone and any clinical situation believed to be under androgen control …
between serum testosterone and any clinical situation believed to be under androgen control …
Screening decreases prostate cancer mortality: 11‐year follow‐up of the 1988 Quebec prospective randomized controlled trial
F Labrie, B Candas, L Cusan, JL Gomez… - The …, 2004 - Wiley Online Library
PURPOSE This clinical trial is aimed at evaluating the impact of prostate cancer screening
on cancer‐specific mortality. SUBJECTS AND METHODS Forty‐six thousand four hundred …
on cancer‐specific mortality. SUBJECTS AND METHODS Forty‐six thousand four hundred …
Beneficial effect of combination hormonal therapy administered prior and following external beam radiation therapy in localized prostate cancer
…, ER Suburu, P Diamond, M Lemay, B Candas… - International Journal of …, 1997 - Elsevier
Purpose : The aim of the present study isto investigate whether combined androgen blockade
associated with radiation therapy for localized prostate cancer decreases at 12 and 24 …
associated with radiation therapy for localized prostate cancer decreases at 12 and 24 …
EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium
…, V Luu-The, Y Mérand, V Giguere, B Candas… - The Journal of steroid …, 1999 - Elsevier
Breast cancer is the most frequent cancer in women while it is the second cause of cancer
death. Estrogens are well recognized to play the predominant role in breast cancer …
death. Estrogens are well recognized to play the predominant role in breast cancer …
Gonadotropin-releasing hormone agonists in the treatment of prostate cancer
…, J Simard, L Cusan, J Gomez, B Candas - Endocrine …, 2005 - academic.oup.com
In 1979, the first prostate cancer patient was treated with a GnRH agonist at the Laval
University Medical Center in Québec City, Canada, thus rapidly leading to the worldwide …
University Medical Center in Québec City, Canada, thus rapidly leading to the worldwide …