Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Obsessive compulsive disorder (OCD) and major depressive disorder (MDD) are common,
often refractory, neuropsychiatric conditions for which new treatment approaches are urgently …

The blood-brain barrier (BBB) is an important factor limiting the effectiveness of central nervous
system (CNS) therapeutics. MR-guided focused ultrasound (MRgFUS) is a noninvasive, …

Background Liquid biopsy is promising for early detection, monitoring of response, and
recurrence of cancer. The blood-brain barrier (BBB) limits the shedding of biomarker, such as cell…

The instruction of a competent living Teacher is doubtless the most efficient means of acquiring
any Language. Supplied with such help the Student requires little more than the subject …

The blood-brain barrier, while fundamental in maintaining homeostasis in the central nervous
system, is a bottleneck to achieving efficacy for numerous therapeutics. Improved brain …

The blood–brain barrier (BBB) protects the brain but is also an important obstacle for the
effective delivery of therapeutics in Alzheimer’s disease and other neurodegenerative disorders…

Background GBA1 mutation is the most common genetic risk factor for Parkinson's disease (PD).
Replacement of the lysosomal enzyme glucocerebrosidase (GCase) slows …

OBJECTIVE Transcranial MR-guided focused ultrasound (MRgFUS) is a minimally invasive
treatment for movement disorders. Considerable interpatient variability in skull transmission …

Alcohol use disorder (AUD) is a highly prevalent, often refractory, medical illness. The
symptoms of AUD are driven by dysfunction in several neurocircuits centered on the nucleus …