[PDF][PDF] Cellular origins of co-stimulator (IL2) and its activity in cytotoxic T lymphocyte responses

J Shaw, B Caplan, V Paetkau, LM Pilarski… - J …, 1980 - scholar.archive.org
MATERIALS AND METHODS Animals and tumor cell lines. All mice were maintained at the
University of Alberta Health Sciences Animal Center. Breeding stock for inbred strains CBA/J …

Resection and ligation of the suprarenal inferior vena cava

BB Caplan, NA Halasz, WE Bloomer - The Journal of Urology, 1964 - auajournals.org
Survival following ligation of the inferior vena cava (IVC) is dependent upon the presence of
a pre-existing collateral venous network or rapid expansion of the normal venous collateral. …

Evaluation of the immunogenicity and protective efficacy of a candidate parainfluenza virus type 3 subunit vaccine in cotton rats

…, PR Wyde, M Ewasyshyn, AM Bonneau, B Caplan… - Vaccine, 1991 - Elsevier
A parainfluenza virus type 3 (PIV3) subunit vaccine consisting of detergent-solubilized,
affinity-purified haemagglutinin-neuraminidase (HN) and fusion (F) surface glycoproteins was …

Properties of sodium dodecyl sulfate-denatured Interleukin 2.

B Caplan, C Gibbs, V Paetkau - Journal of immunology (Baltimore …, 1981 - journals.aai.org
Murine Interleukin 2 (IL2) was denatured with sodium dodecyl sulfate (SDS) with or without
concomitant reduction of disulfide bonds. Between 50 and 100% of the activity was …

Translation of lymphocyte mRNA into biologically-active Interleukin 2 in oocytes.

RC Bleackley, B Caplan, C Havele… - … (Baltimore, Md.: 1950 …, 1981 - journals.aai.org
A variant line of murine T lymphoma EL4 produces high levels of the lymphokine Interleukin
2 (IL 2) when it is stimulated with phorbol myristate acetate. We have extracted poly A+ RNA …

High-level secretion of interleukin 2 by a subset of proliferating thymic lymphoblasts.

B Caplan, E Rothenberg - Journal of immunology (Baltimore, Md …, 1984 - journals.aai.org
We have characterized the thymocytes that can be induced to secrete interleukin 2 (IL 2) after
polyclonal stimulation with Con A. For maximal activation, an important adjunct to the Con …

Interleukin-2 does not induce murine B cells to secrete Ig.

E Pure, PC Isakson, V Paetkau, B Caplan… - … (Baltimore, Md.: 1950 …, 1982 - journals.aai.org
We previously defined two T cell-derived lymphokines, BDCF mu and BCDF gama, which
induce B cell differentiation in the absence of IL 2. Although these studies indicated that IL 2 …

Urinary lactic acid dehydrogenase activity in the diagnosis of urologic neoplasms

DA Lee, ATK Cockett, BM Caplan… - The Journal of …, 1966 - auajournals.org
Roche G, Brugerolle B, Straczek J, Bertrand F, Hurault de Ligny B, Gérard A, Presles O, Canton
P and Dureux J (1983) Étude de la valeur des dosages de quatre activités enzymatiques …

Interleukin 2 in cell‐mediated immune responses

V Paetkau, J Shaw, B Caplan… - Journal of …, 1980 - Wiley Online Library
The lymphokine Interleukin 2 (IL2) restores T cell responses in a number of in vitro systems
where immunogenicity has been compromised. UV irradiation of the stimulating allogeneic …

Preliminary validation of an activation assay for ex vivo activated T cells utilized in cancer immunotherapy

…, GC du Moulin, V Liu, B Caplan… - Biotechnology and …, 1994 - Wiley Online Library
An in vitro assay that measures the activation level of ex vivo activated (EVA) T cells currently
being used in the adoptive immunotherapy of metastatic renal cell carcinoma has been …