User profiles for B. E. Nolan
 | Brian E NolanAnn & Robert H. Lurie Children's Hospital of Chicago Verified email at luriechildrens.org Cited by 1671 |
Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence
…, L Lewis-Ximenez, V Kasprowicz, BE Nolan… - Journal of Experimental …, 2012 - rupress.org
Vigorous proliferative CD4 + T cell responses are the hallmark of spontaneous clearance of
acute hepatitis C virus (HCV) infection, whereas comparable responses are absent in …
acute hepatitis C virus (HCV) infection, whereas comparable responses are absent in …
High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome
…, J Schulze zur Wiesch, T Kuntzen, BE Nolan… - Journal of …, 2008 - Am Soc Microbiol
We monitored expression of PD-1 (a mediator of T-cell exhaustion and viral persistence) on
hepatitis C virus (HCV)-specific CD8 + and CD4 + T cells from blood and liver during acute …
hepatitis C virus (HCV)-specific CD8 + and CD4 + T cells from blood and liver during acute …
[HTML][HTML] Juvenile dermatomyositis: new clues to diagnosis and therapy
LM Pachman, BE Nolan, D DeRanieri… - Current treatment options …, 2021 - Springer
Purpose of review To identify clues to disease activity and discuss therapy options. Recent
findings The diagnostic evaluation includes documenting symmetrical proximal muscle …
findings The diagnostic evaluation includes documenting symmetrical proximal muscle …
Spontaneous control of HCV is associated with expression of HLA-B* 57 and preservation of targeted epitopes
AY Kim, T Kuntzen, J Timm, BE Nolan, MA Baca… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: HLA class I alleles are linked to spontaneous control of hepatitis C
virus (HCV) and human immunodeficiency virus−1, but for HCV the roles of particular alleles …
virus (HCV) and human immunodeficiency virus−1, but for HCV the roles of particular alleles …
Reduced frequencies of NKp30+ NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance
BACKGROUND & AIMS: While the majority of HCV-infected patients progress to chronic
hepatitis, a small fraction of individuals are able to clear the virus. Resolution of infection occurs …
hepatitis, a small fraction of individuals are able to clear the virus. Resolution of infection occurs …
Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responses
…, S Glauzy, JN Schickel, M Trofa, BE Nolan… - Journal of Allergy and …, 2019 - Elsevier
Background The lack of pathogen-protective, isotype-switched antibodies in patients with
common variable immunodeficiency (CVID) suggests germinal center (GC) hypoplasia, yet a …
common variable immunodeficiency (CVID) suggests germinal center (GC) hypoplasia, yet a …
Constrained chromatin accessibility in PU. 1-mutated agammaglobulinemia patients
The pioneer transcription factor (TF) PU.1 controls hematopoietic cell fate by decompacting
stem cell heterochromatin and allowing nonpioneer TFs to enter otherwise inaccessible …
stem cell heterochromatin and allowing nonpioneer TFs to enter otherwise inaccessible …
[PDF][PDF] Human leukocyte antigen–associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution
CD8 + T cell responses play a key role in governing the outcome of hepatitis C virus (HCV)
infection, and viral evolution enabling escape from these responses may contribute to the …
infection, and viral evolution enabling escape from these responses may contribute to the …
Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution
…, T Kuntzen, V Fleming, BE Nolan… - Journal of …, 2010 - Am Soc Microbiol
Hepatitis C virus (HCV)-specific CD8 + T cells in persistent HCV infection are low in frequency
and paradoxically show a phenotype associated with controlled infections, expressing the …
and paradoxically show a phenotype associated with controlled infections, expressing the …
pH-dependent helix folding dynamics of poly-glutamic acid
…, S Sharma, SA Petty, EA Fouts, CJ Palmer, BE Nolan… - Chemical Physics, 2013 - Elsevier
Poly-L-glutamic acid (PGA) is an ideal model system for investigating the transition between
α-helical and random coil peptide conformations, since its secondary structure is highly …
α-helical and random coil peptide conformations, since its secondary structure is highly …