Background Hospitals have difficulty justifying the expense of maintaining trauma centers
without strong evidence of their effectiveness. To address this gap, we examined differences in …

Importance Although wait times for hip fracture surgery have been linked to mortality and are
being used as quality-of-care indicators worldwide, controversy exists about the duration of …

ContextThe premise underlying regionalization of trauma care is that larger volumes of trauma
patients cared for in fewer institutions will lead to improved outcomes. However, whether …

ContextDespite calls for wider national implementation of an integrated approach to trauma
care, the effectiveness of this approach at a regional or state level remains unproven.…

… Nathens, MD, MPH, Harborview Medical Center, Box 359796, 325 9th Ave., Seattle, WA
98104-2499. … Nathens AB, Bitar R, Davreux C, et al. Pyrrolidine dithiocarbamate …

Although existing guidelines support the utilization of intracranial pressure (ICP) monitoring
in patients with traumatic brain injury (TBI), the evidence suggesting benefit is limited. To …

A cornerstone of modern biomedical research is the use of mouse models to explore basic
pathophysiological mechanisms, evaluate new therapeutic approaches, and make go or no-…

Background: The cost of trauma center care is high, raising questions about the value of a
regionalized approach to trauma care. To address these concerns, we estimate 1-year and …

… MD a, b, d ; Eskicioglu, Cagla MD a, b, d ; Nathens, Avery B. MD, FACS a, b ; Fenech,
Darlene S. MD a, b, d ; Laflamme, Claude MD c ; McLean, Richard F. … Avery B Nathens …

Evidence-based guidelines for managing patients with intra-abdominal infection were prepared
by an Expert Panel of the Surgical Infection Society and the Infectious Diseases Society …