Background Radiotherapy after mastectomy to treat early breast cancer has been known
since the 1940s to reduce rates of local relapse. However, the routine use of postoperative …

Background: The British Columbia randomized radiation trial was designed to determine
the survival impact of locoregional radiation therapy in premenopausal patients with lymph …

Background The course of advanced renal cell carcinoma is extremely variable, ranging
from spontaneous remission to disease progression refractory to chemotherapy. …

Background and Design: Basal cell carcinoma (BCC) of the skin is the most common
neoplasm in white populations, and solar radiation is generally accepted to be the dominant …

Background In the treatment of lung cancer, the best outcome is achieved when the lesion
is discovered in the intraepithelial (preinvasive) stage. However, intraepithelial neoplastic …

Purpose Adjuvant! ( www.adjuvantonline.com ) is a web-based tool that predicts 10-year
breast cancer outcomes with and without adjuvant systemic therapy, but it has not been …

Drug resistance continues to be a major factor in limiting the effectiveness of cancer
chemotherapy. Evidence from a variety of sources implicates a genetic basis for most drug-resistant …

Anaplastic large cell lymphoma (ALCL) is an aggressive lymphoma that is frequently
associated with the t(2;5)(p23;q35), resulting in expression of a fusion protein, nucleophosmin-…

The prognostic significance of Bcl-2 protein expression and bcl-2 gene rearrangement in
diffuse large cell lymphomas (DLCL) is controversial. Bcl-2 protein expression prevents …

Recently, there has been a growing number of studies applying image processing techniques
to analyze melanocytic lesions for atypia and possible malignancy and for total-body mole …