The frequency of pathogenic/likely pathogenic (P/LP) germ line variants in patients with
myelodysplastic syndrome (MDS) diagnosed at age 40 years or less is 15% to 20%. However, …

Colony-stimulating factor 3 receptor (CSF3R) encodes the receptor for granulocyte colony-stimulating
factor (G-CSF), a cytokine vital for granulocyte proliferation and differentiation. …

Inherited predisposition to haematopoietic malignancies, due to deleterious germline variants
in a variety of genes, is an important clinical entity with implications for the health and …

With improvements in DNA sequencing technologies and the consequent reduction in costs,
next generation sequencing is being utilized increasingly in panel-based testing to perform …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare CD4+ CD56+ myeloid
malignancy that is challenging to diagnose and treat. BPDCN typically presents with nonspecific …

Myeloid neoplasms with germline predisposition have been recognized increasingly over
the past decade with numerous newly described disorders. Penetrance, age of onset, …

Acute myeloid leukemia with germline CEBPA mutation is a subtype of acute myeloid leukemia
that is associated with a favorable prognosis. Most of the reported cases of acute myeloid …

Abstract Changes in the molecular orientation, melting behavior, and percent crystallinity of
the individual components in a fibrous blend of isotactic polypropylene (iPP) and high‐…

… Amy M. Trottier, Emad Massoud and Timothy Brown … Amy Trottier drafted the article, which
all the authors revised. All the authors approved the final version submitted for publication. …

Although germline predisposition to hematologic malignancy is gaining increasing recognition
and more patients with acute myeloid leukemia and myelodysplastic syndrome may have …